4-(Chloromethyl)-2,2-dimethyl-1,2-dihydrobenzo[f]isoquinoline

Base Information

Chemical Name:4-(Chloromethyl)-2,2-dimethyl-1,2-dihydrobenzo[f]isoquinoline
CAS No.:217480-50-7
Molecular Formula:C16H16ClN
Molecular Weight:257.75800
Hs Code.:
DSSTox Substance ID:DTXSID40353840
Wikidata:Q82131652
Mol file:217480-50-7.mol

Synonyms:217480-50-7;4-(chloromethyl)-2,2-dimethyl-1,2-dihydrobenzo[f]isoquinoline;4-(chloromethyl)-2,2-dimethyl-1H-benzo[f]isoquinoline;Benz[f]isoquinoline, 4-(chloromethyl)-1,2-dihydro-2,2-dimethyl-;DTXSID40353840;STK763145;AKOS000672111;AG-690/36164027;4-chloromethyl-2,2-dimethyl-1,2-dihydrobenzo[f]isoquinoline

Suppliers and Price of 4-(Chloromethyl)-2,2-dimethyl-1,2-dihydrobenzo[f]isoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-(Chloromethyl)-2,2-dimethyl-1,2-dihydrobenzo[f]isoquinoline

Chemical Property:

PSA：12.36000
LogP:3.63800
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:257.0971272
Heavy Atom Count:18
Complexity:347

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(CC2=C(C=CC3=CC=CC=C23)C(=N1)CCl)C

Technology Process of 4-(Chloromethyl)-2,2-dimethyl-1,2-dihydrobenzo[f]isoquinoline

There total 1 articles about 4-(Chloromethyl)-2,2-dimethyl-1,2-dihydrobenzo[f]isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 34577-38-3
2-Methyl-1-(α-naphthyl)-2-propanol

: 107-14-2
chloroacetonitrile

: 217480-50-7
4-chloromethyl-2,2-dimethyl-1,2-dihydrobenzo[f]isoquinoline

Guidance literature:: With sulfuric acid; In benzene; at 10 - 60 ℃; for 0.5h;
DOI:10.1007/BF02465771

Reference yield: 83.0%

: 108-98-5
thiophenol

: 217480-50-7
4-chloromethyl-2,2-dimethyl-1,2-dihydrobenzo[f]isoquinoline

: 2,2-dimethyl-4-phenylthio-1,2-dihydrobenzo[f]isoquinoline

Guidance literature:: With sodium hydroxide; In ethanol;
DOI:10.1023/A:1015343426495

Reference yield:

: 150-76-5
4-methoxy-phenol

: 217480-50-7
4-chloromethyl-2,2-dimethyl-1,2-dihydrobenzo[f]isoquinoline

: 4-(4-methoxy-phenoxymethyl)-2,2-dimethyl-1,2-dihydro-benzo[f]isoquinoline

Guidance literature:: With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In dichloromethane; at 60 - 70 ℃; for 1h;
DOI:10.1023/A:1015343426495