2-Pyridinecarboxaldehyde, 2-pyridinylhydrazone, (Z)-

Base Information

• Chemical Name: 2-Pyridinecarboxaldehyde, 2-pyridinylhydrazone, (Z)-
• CAS No.: 21945-38-0
• Molecular Formula: C11H10N4
• Molecular Weight: 198.227
• Mol file: 21945-38-0.mol

Synonyms:pyridine-2-carbaldehyde 2-pyridylhydrazone;Z-pyridine-2-carbaldehyde 2-pyridylhydrazone;N-Pyridin-2-yl-N'-[1-pyridin-2-yl-meth-(Z)-ylidene]-hydrazine;

Chemical Property of 2-Pyridinecarboxaldehyde, 2-pyridinylhydrazone, (Z)-

Chemical Property:

• PSA: 50.17000
• LogP: 1.99560

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Pyridinecarboxaldehyde, 2-pyridinylhydrazone, (Z)-

There total 12 articles about 2-Pyridinecarboxaldehyde, 2-pyridinylhydrazone, (Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

E-pyridine-2-carbaldehyde 2-pyridylhydrazone (21945-37-9,2215-33-0) → Z-pyridine-2-carbaldehyde 2'-pyridylhydrazone (21945-38-0,2215-33-0)

Guidance literature:

In methanol; for 0.333333h; UV-irradiation;

DOI:10.1002/chem.201002308

Reference yield:

pyrid-2-ylhydrazine (4930-98-7) + (Z)-2-pyridine-carbaldehyde phenylhydrazone (30915-37-8) → E-pyridine-2-carbaldehyde 2-pyridylhydrazone (21945-37-9,2215-33-0) + Z-pyridine-2-carbaldehyde 2'-pyridylhydrazone (21945-38-0,2215-33-0) + phenylhydrazine (100-63-0)

Guidance literature:

With scandium tris(trifluoromethanesulfonate); In d⁽⁴⁾-methanol; at 45 ℃;

DOI:10.1002/chem.201002308

Reference yield:

2-aminopyridine (504-29-0) → Z-pyridine-2-carbaldehyde 2'-pyridylhydrazone (21945-38-0,2215-33-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 60 percent / 47percent HBr, Br₂, aq. NaCN / 0 °C

2: 54 percent / N₂H₄*H₂O / 4 h / Heating

3: 10percent HCl / ethanol / 2 h / Heating

With hydrogenchloride; sodium cyanide; hydrogen bromide; bromine; hydrazine hydrate; In ethanol;

DOI:10.1016/S0223-5234(98)80008-1

upstream raw materials:

E-pyridine-2-carbaldehyde 2-pyridylhydrazone

pyridine-2-carbaldehyde

pyrid-2-ylhydrazine

2-aminopyridine

Downstream raw materials:

E-pyridine-2-carbaldehyde 2-pyridylhydrazone

5-(2'-pyridyl)-s-triazolo<4,3-a>pyridine

N'-acetyl-N'-(4-nitrophenyl)pyridine-2-carbohydrazide

2-[(2E)-2-benzylidenehydrazinyl]pyridine