4-(4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1-CARBONYL)-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER

Base Information

Chemical Name:4-(4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1-CARBONYL)-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER
CAS No.:220031-94-7
Molecular Formula:C24H35N3O5
Molecular Weight:445.55200
Hs Code.:
Mol file:220031-94-7.mol

Synonyms:1-(1-benzyloxycarbonyl-4-piperidinylcarbonyl)-4-(t-butoxycarbonylamino)piperidine;Benzene,[(1-phenylbutoxy)methyl];1-(1-benzyloxybutyl)benzene;

Suppliers and Price of 4-(4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1-CARBONYL)-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-(4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1-CARBONYL)-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER 95.00%
5MG
$ 502.05

Total 3 raw suppliers

Chemical Property of 4-(4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1-CARBONYL)-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER

Chemical Property:

PSA：88.18000
LogP:3.81760

Purity/Quality:

97% ^*data from raw suppliers

4-(4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1-CARBONYL)-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1-CARBONYL)-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER

There total 5 articles about 4-(4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1-CARBONYL)-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 10314-98-4
1-benzyloxycarbonylpiperidine-4-carboxylic acid

: 73874-95-0
(piperidin-4-yl)carbamic acid tert-butyl ester

: 220031-94-7
1-(1-benzyloxycarbonyl-4-piperidinylcarbonyl)-4-(t-butoxycarbonylamino)piperidine

Guidance literature:: With thionyl chloride; triethylamine; In dichloromethane;

Reference yield:

: 498-94-2
isonipecotic acid

: 220031-94-7
1-(1-benzyloxycarbonyl-4-piperidinylcarbonyl)-4-(t-butoxycarbonylamino)piperidine

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / 15 h / 20 °C

2: SOCl₂ / CH₂Cl₂ / 1 h / Heating

3: Et₃N / 4 h / 20 °C

With thionyl chloride; triethylamine; In dichloromethane;
DOI:10.1016/S0960-894X(02)00060-4

Reference yield:

: 10314-98-4
1-benzyloxycarbonylpiperidine-4-carboxylic acid

: 220031-94-7
1-(1-benzyloxycarbonyl-4-piperidinylcarbonyl)-4-(t-butoxycarbonylamino)piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / CH₂Cl₂ / 1 h / Heating

2: Et₃N / 4 h / 20 °C

With thionyl chloride; triethylamine; In dichloromethane;
DOI:10.1016/S0960-894X(02)00060-4