1-(((5-(4-Chlorophenyl)-2-furanyl)-methylene)amino)-3-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-2,4-imidazolidinedione dihydrochloride

Base Information

• Chemical Name: 1-(((5-(4-Chlorophenyl)-2-furanyl)-methylene)amino)-3-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-2,4-imidazolidinedione dihydrochloride
• CAS No.: 149889-02-1
• Molecular Formula: C₂₃H₂₈ClN₅O₄*2ClH
• Molecular Weight: 546.881
• Mol file: 149889-02-1.mol

Synonyms:1-(((5-(4-chlorophenyl)-2-furanyl)-methylene)amino)-3-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-2,4-imidazolidinedione dihydrochloride;NE 10133;NE-10133

Chemical Property of 1-(((5-(4-Chlorophenyl)-2-furanyl)-methylene)amino)-3-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-2,4-imidazolidinedione dihydrochloride

Chemical Property:

• Vapor Pressure: 3.92E-17mmHg at 25°C
• Boiling Point: 637.6°Cat760mmHg
• Flash Point: 339.4°C
• Density: g/cm³
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 9
• Exact Mass: 545.136338
• Heavy Atom Count: 35
• Complexity: 694

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN(CCN1CCCN2C(=O)CN(C2=O)N=CC3=CC=C(O3)C4=CC=C(C=C4)Cl)CCO.Cl.Cl
• Isomeric SMILES: C1CN(CCN1CCCN2C(=O)CN(C2=O)/N=C/C3=CC=C(O3)C4=CC=C(C=C4)Cl)CCO.Cl.Cl

Technology Process of 1-(((5-(4-Chlorophenyl)-2-furanyl)-methylene)amino)-3-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-2,4-imidazolidinedione dihydrochloride

There total 2 articles about 1-(((5-(4-Chlorophenyl)-2-furanyl)-methylene)amino)-3-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-2,4-imidazolidinedione dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2-hydroxyethyl)piperazine (103-76-4) + 1-[[[5-(4-chlorophenyl)-2-furanyl]methylene]amino]-3-(3-chloropropyl)-2,4-imidazolidinedione → NE 10133 (149889-02-1)

Guidance literature:

With hydrogenchloride; sodium hydrogencarbonate; In N-methyl-acetamide;

Reference yield:

1-[[[5-(4-chlorophenyl)-2-furanyl]methylene]-amino]-3-[3-[4-(2-hydroxyethyl)-1-piperazynyl]propyl]-2,4-imidazolidinedione → 1-[[[5-(4-chlorophenyl)-2-furanyl]methylene]-amino]-3-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]-2,4-imidazolidinedione dihydrochloride (149889-02-1)

Guidance literature:

With hydrogenchloride; In ethanol;

upstream raw materials:

1-(2-hydroxyethyl)piperazine

Refernces

• 1、 -. "4-oxocyclic ureas useful as antiarrhythmic and antifibrillatory agents". . . Retrieved 2008/06/13.