N,N-Dimethyloleamide

Base Information

• Chemical Name: N,N-Dimethyloleamide
• CAS No.: 2664-42-8
• Deprecated CAS: 61461-82-3
• Molecular Formula: C20H39 N O
• Molecular Weight: 309.536
• European Community (EC) Number: 220-193-7
• NSC Number: 68869
• UNII: T5FNY9JT2L
• DSSTox Substance ID: DTXSID2040288
• Nikkaji Number: J36.615C
• Wikidata: Q27289696
• ChEMBL ID: CHEMBL15451
• Mol file: 2664-42-8.mol

Synonyms:N,N-Dimethyloleamide;2664-42-8;Hallcomid M 18OL;N,N-Dimethyl oleylamide;N,N-Dimethyl-cis-9-octadecenamide;(Z)-N,N-Dimethyl-9-octadecenamide;UNII-T5FNY9JT2L;Oleamide, N,N-dimethyl-;T5FNY9JT2L;9-Octadecenamide, N,N-dimethyl-, (Z)-;EINECS 220-193-7;NSC 68869;NSC-68869;9-Octadecenamide, N,N-dimethyl-, (9Z)-;(Z)-N,N-dimethyloctadec-9-enamide;NSC68869;Oleamide,N-dimethyl-;SCHEMBL79558;CHEMBL15451;C20H39NO;DTXSID2040288;9-Octadecenamide,N-dimethyl-, (Z)-;9-OCTADECENAMIDE, N,N-DIMETHYL-, (Z);Q27289696

Chemical Property of N,N-Dimethyloleamide

Chemical Property:

• Vapor Pressure: 3.37E-07mmHg at 25°C
• Melting Point: -8 °C
• Refractive Index: 1.464
• Boiling Point: 418.1°Cat760mmHg
• PKA: -0.43±0.70(Predicted)
• Flash Point: 170.4°C
• PSA: 20.31000
• Density: 0.867g/cm³
• LogP: 6.11210
• XLogP3: 7.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 15
• Exact Mass: 309.303164868
• Heavy Atom Count: 22
• Complexity: 271

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCCCCCC=CCCCCCCCC(=O)N(C)C
• Isomeric SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)N(C)C

Technology Process of N,N-Dimethyloleamide

There total 5 articles about N,N-Dimethyloleamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(Z)-9-octadecenoyl chloride (112-77-6) + dimethyl amine (124-40-3) → N,N-dimethyl oleamide (2664-42-8)

Guidance literature:

In benzene; for 1h; Ambient temperature;

DOI:10.1271/bbb1961.47.53

Reference yield: 96.0%

cis-Octadecenoic acid (112-80-1,2027-47-6) + dimethyl amine (124-40-3) → N,N-dimethyl oleamide (2664-42-8)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; (bis-(2-methoxyethyl)amino)sulfur trufluoride; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1016/j.tetlet.2005.10.068

Reference yield: 82.0%

→ N,N-dimethyl oleamide (2664-42-8)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 - 20 ℃; for 2h; Inert atmosphere;

In dichloromethane;

upstream raw materials:

(Z)-9-octadecenoyl chloride

N,N-dimethyl-formamide

dimethyl amine

cis-Octadecenoic acid

Downstream raw materials:

Oleic aldehyde

N,N-dimethyl-N-oleylamine

oleoyl alcohol

Refernces

• 1、 -. "A METHOD OF TREATING PERIPHERAL INFLAMMATORY DISEASE". Paragraph 0078-0084; 0094-0095. . Retrieved 2016/12/01.
• 2、 Oba, Gabriel,Coleman, Bridgett E.,Hart, David J.,Zakin, Jacques,Zhang, Ying,Kawaguchi, Yasuo,Talmon, Yeshayahu. "Synthesis of aminimides derived from oleic acid: a new family of drag-reducing surfactants". . p. 10193 - 10201. Retrieved 2007/10/03.