Methyl 4-oxo-2-phenyl-1,4-dihydroquinoline-3-carboxylate

Base Information

Chemical Name:Methyl 4-oxo-2-phenyl-1,4-dihydroquinoline-3-carboxylate
CAS No.:223565-36-4
Molecular Formula:C₁₇H₁₃NO₃
Molecular Weight:279.295
Hs Code.:
DSSTox Substance ID:DTXSID00454408
Nikkaji Number:J1.076.277D,J2.108.096I
Wikidata:Q82275918
Mol file:223565-36-4.mol

Synonyms:223565-36-4;Methyl 4-oxo-2-phenyl-1,4-dihydroquinoline-3-carboxylate;AGN-PC-0OIKVX;DTXSID00454408;2-Phenyl-4-hydroxyquinoline-3-carboxylic acid methyl ester;1,4-Dihydro-2-phenyl-4-oxoquinoline-3-carboxylic acid methyl ester

Suppliers and Price of Methyl 4-oxo-2-phenyl-1,4-dihydroquinoline-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Methyl 4-oxo-2-phenyl-1,4-dihydroquinoline-3-carboxylate

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:279.08954328
Heavy Atom Count:21
Complexity:463

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C(NC2=CC=CC=C2C1=O)C3=CC=CC=C3

Technology Process of Methyl 4-oxo-2-phenyl-1,4-dihydroquinoline-3-carboxylate

There total 8 articles about Methyl 4-oxo-2-phenyl-1,4-dihydroquinoline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 2556-46-9,141417-98-3
N,N'-diphenylbenzamidine

: 1186-73-8
methanetricarboxylic acid trimethyl ester

: 223565-36-4,816450-72-3
4-oxo-2-phenyl-1,4-dihydroquinoline-3-carboxylic acid methyl ester

Guidance literature:: In tetralin; for 4h; Heating;
DOI:10.1246/bcsj.72.503

Reference yield: 76.0%

: 118-48-9
isatoic anhydride

: 4891-38-7
phenylpropynoic acid methyl ester

: 223565-36-4,816450-72-3
4-oxo-2-phenyl-1,4-dihydroquinoline-3-carboxylic acid methyl ester

Guidance literature:: With tert.-butylhydroperoxide; caesium carbonate; In dimethyl sulfoxide; at 100 ℃;
DOI:10.1021/acs.orglett.8b01645

Reference yield: 75.0%

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 4891-38-7
phenylpropynoic acid methyl ester

: 223565-36-4,816450-72-3
4-oxo-2-phenyl-1,4-dihydroquinoline-3-carboxylic acid methyl ester

Guidance literature:: With tert.-butylhydroperoxide; caesium carbonate; In dimethyl sulfoxide; at 100 ℃; for 12h; Reagent/catalyst; Sealed tube;
DOI:10.1021/acs.orglett.8b01645