2-(2-Methylphenoxy)acetamide

Base Information

• Chemical Name: 2-(2-Methylphenoxy)acetamide
• CAS No.: 22560-43-6
• Molecular Formula: C9H11NO2
• Molecular Weight: 165.192
• Hs Code.: 2924299090
• European Community (EC) Number: 652-747-2
• DSSTox Substance ID: DTXSID80352594
• Wikidata: Q82129833
• Mol file: 22560-43-6.mol

Synonyms:2-(2-methylphenoxy)acetamide;22560-43-6;2-(o-Tolyloxy)acetamide;(2-methylphenoxy)acetamide;2-o-Tolyloxy-acetamide;SCHEMBL1395765;DTXSID80352594;QPCWSKDUWIYHBQ-UHFFFAOYSA-N;Acetamide, 2-(2-methylphenoxy)-;MFCD01008958;STK002216;AKOS000299301;BB 0244334;CS-0293050;Z19733874

Chemical Property of 2-(2-Methylphenoxy)acetamide

Chemical Property:

• PSA: 53.31000
• LogP: 2.00880
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 165.078978594
• Heavy Atom Count: 12
• Complexity: 159

Purity/Quality:

2-(2-METHYLPHENOXY)ACETAMIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1OCC(=O)N

Technology Process of 2-(2-Methylphenoxy)acetamide

There total 11 articles about 2-(2-Methylphenoxy)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

→ ortho-methylphenoxyacetamide (22560-43-6)

Guidance literature:

With dihydrogen peroxide; sodium hydroxide; In water; at 80 ℃; for 4h;

Reference yield:

ortho-cresol (95-48-7,77504-84-8) + Chloroacetamide (79-07-2) → ortho-methylphenoxyacetamide (22560-43-6)

Guidance literature:

With sodium; In ethanol;

DOI:10.1016/j.bmcl.2010.01.030

Reference yield:

4-o-tolyloxymethyl-3H-oxazol-2-one (22560-40-3) → ortho-methylphenoxyacetamide (22560-43-6)

Guidance literature:

With 4-nitroperbenzoic acid; In chloroform; at 0 - 5 ℃;

upstream raw materials:

o-methylphenoxyacetic acid

urea

4-o-tolyloxymethyl-3H-oxazol-2-one

(2-methylphenoxy)acetyl chloride

Downstream raw materials:

β-(2-methylphenoxy)ethylamine

(o-tolyloxy)acetonitrile

o-methylphenoxyacetic acid