Cyclohex-3-en-1-amine hydrochloride

Base Information

• Chemical Name: Cyclohex-3-en-1-amine hydrochloride
• CAS No.: 22615-33-4
• Molecular Formula: C6H11N.ClH
• Molecular Weight: 133.61900
• Hs Code.: 2921300090
• European Community (EC) Number: 825-770-2
• Mol file: 22615-33-4.mol

Synonyms:22615-33-4;cyclohex-3-en-1-amine hydrochloride;Cyclohex-3-enylamine hydrochloride;Cyclohex-3-enamine HCl;cyclohex-3-en-1-amine;hydrochloride;Cyclohex-3-enamine hydrochloride;MFCD10566844;(R)-Cyclohex-3-enylamine hydrochloride;3-Cyclohexen-1-amine, hydrochloride;3-Cyclohexenamine Hydrochloride;Cyclohex-3-enaminehydrochloride;SCHEMBL9980432;XAA61533;AB8978;AKOS026745000;SB32965;SB35600;AS-44934;SY187909;3-Cyclohexen-1-aMine, hydrochloride (1:1);EN300-80850;F8888-7144

Chemical Property of Cyclohex-3-en-1-amine hydrochloride

Chemical Property:

• PSA: 26.02000
• LogP: 2.55610
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 133.0658271
• Heavy Atom Count: 8
• Complexity: 76.2

Purity/Quality:

97% ^*data from raw suppliers

Cyclohex-3-enamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(CC=C1)N.Cl

Technology Process of Cyclohex-3-en-1-amine hydrochloride

There total 5 articles about Cyclohex-3-en-1-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

4-(tert-butoxycarbonylamino)-1-cyclohexene (135262-85-0) → cyclohex-3-en-1-ylamine hydrochloride (22615-33-4)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; Inert atmosphere;

DOI:10.1002/anie.201304186

Reference yield:

1,2,5,6-tetrahydrobenzoic acid (4771-80-6) → cyclohex-3-en-1-ylamine hydrochloride (22615-33-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / thionyl chloride / Ambient temperature

With thionyl chloride;

DOI:10.1002/jhet.5570270652

Reference yield:

1-isocyano-3-cyclohexene (4103-88-2) → cyclohex-3-en-1-ylamine hydrochloride (22615-33-4)

Guidance literature:

Multi-step reaction with 2 steps

1: copper(l) chloride / Inert atmosphere

2: hydrogenchloride / 1,4-dioxane / Inert atmosphere

With hydrogenchloride; copper(l) chloride; In 1,4-dioxane;

DOI:10.1002/anie.201304186

upstream raw materials:

cyclohex-3-enecarbonyl chloride

1,2,5,6-tetrahydrobenzoic acid

1-isocyano-3-cyclohexene

cyclohex-3-enylmethanol

Downstream raw materials:

N-<(Trifluoroacetyl)amino>cyclohex-3-ene