4103-88-2

Upstream product

• 4771-80-6 1,2,5,6-tetrahydrobenzoic acid 
• 53102-81-1 3-Cyclohexencarbonylazid 
• 72581-32-9 cyclohex-3-enylmethanol 

Downstream Products

• 52068-90-3 C₂₄H₃₀N₄O₄S 
• 22782-34-9 C₂₄H₃₀N₄O₄S 
• 89622-07-1 7-azabicyclo[3.2.1]oct-3-en-6-one 
• 226883-07-4 N-(cyclohex-3-enyl)-2,2,2-trichloroacetamide 
• 847798-81-6 1,3-di(cyclohex-3-enyl)urea 
• 50845-83-5 N-(cyclohex-3-enyl)acetamide 
• 126525-34-6 N-(cyclohex-3-enyl)acrylamide 
• 135262-85-0 4-(tert-butoxycarbonylamino)-1-cyclohexene 
• 22615-33-4 cyclohex-3-en-1-ylamine hydrochloride 
• 210574-45-1 benzyl N-(cyclohex-3-en-1-yl)carbamate 
• 59556-17-1 gabaculin 
• 89622-09-3 (1S,2R,3R,5S)-2,3-Dibromo-5-tert-butoxycarbonylamino-cyclohexanecarboxylic acid methyl ester 
• 89622-08-2 (1R,5R)-5-tert-Butoxycarbonylamino-cyclohex-2-enecarboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of Pyridazine and Pyrrole Analogues of 2-Aminotetralin as Potential Dopaminergics

Syntheses of pyridazine and pyrrole analogues of 2-aminotetralin starting from 3-cyclohexene-1-carboxylic acid are reported. All syntheses involve the following key steps: Curtius rearrangement for amine functionality, inverse electron demand Diels–Alder

Palladium- and ruthenium-catalyzed cycloisomerization of enynamides and enynhydrazides: A rapid approach to diverse azacyclic frameworks

I want to ride my azacycle: The title reaction of enynamides affords a wide diversity of azacycles. The reactions are high-yielding, highly stereoselective, and proceed rapidly under mild reaction conditions. Equivalent transformations using enynhydrazides offer new routes to pyrazole and indazole scaffolds. Boc=tert-butoxycarbonyl, EWG=electron-withdrawing group, Ns=4-nitrobenzenesulfonyl, Ts=4-toluenesulfonyl. Copyright

PROCESS FOR THE PREPARATION OF PLEUROMUTILINS

Process for the preparation of a Compound of formula I in the form of a single stereoisomer in crystalline form, comprising deprotecting the amine group in a Compound of formula IIa or in a mixture of a compound of formula IIa With a compound of formula IIb and isolating a Compound of formula I from the reaction mixture; Compounds and salts of Compounds of formula I in crystalline form; pharmaceutical compositions comprising such salts; processes for the preparation of intermediates and intermediates in a process for the preparation of a Compound of formula I.

Synthesis of new 7-azabicyclo[2.2.1]heptane derivatives

The synthesis of new 7-azabicyclo[2.2.1]heptane derivatives has been achieved in a four-step synthetic sequence, starting from readily available cyclohex-3-enecarboxylic acid, Curtius reaction, stereoselective bromination leading to major benzyl(cis-3, tr

Scope of the directed dihydroxylation: Application to cyclic homoallylic alcohols and trihaloacetamides

The synthesis and directed dihydroxylation of a range of cyclic alkenes was investigated. Both homoallylic alcohols and homoallylic trihaloacetamides were found to be efficient directing groups, giving rise to good to excellent levels of remote asymmetric induction with OsO4-TMEDA. Interestingly, in all cases examined, trifluoroacetamides were found to be superior to trichloroacetamides as directing groups and an argument is presented which rationalises this observation.

No-flow reworkable epoxy underfills for flip-chip applications

A no-flow reworkable epoxy underfill is provided for use in an electronic packaged system which incorporates an integrated circuit, an organic printed wire board, and at least one eutectic solder joint formed therebetween. An exemplary embodiment of the e

Novel guanidinobenzamides

Compounds of formula IA and IB are new where the variables R1 through R10 have the values set forth herein. Such compounds have use in treating diseases such as obesity and type II diabetes, and may be provided as pharmaceutical form

Thermally degradable epoxy underfills for flip-chip applications

A reworkable epoxy underfill is provided for use in an electronic packaged system which incorporates an integrated circuit, an organic printed wire board, and at least one eutectic solder joint formed therebetween. An exemplary embodiment of the encapsula

REGIOSELECTIVE SYNTHESIS OF (+/-)-GABACULINE HYDROCHLORIDE

3-Cyclohexenecarboxylic acid (2) has been functionalized to the protected amino acid 5 in a novel reaction sequence, the crucial step being the acid catalysed cyclization of the γ,δ-unsaturated isocyanate 3 to the bicyclic lactam 4. 5 was converted into gabaculine hydrochloride (l HCl).