1-N-BOC-4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDINE

Base Information

Chemical Name:1-N-BOC-4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDINE
CAS No.:235109-63-4
Molecular Formula:C16H22ClNO3
Molecular Weight:311.809
Hs Code.:
Mol file:235109-63-4.mol

Synonyms:

Suppliers and Price of 1-N-BOC-4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-BOC-4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDINE 95.00%
5MG
$ 500.03

Acrotein
1-Boc-4-(4-chlorophenyl)-4-hydroxypiperidine 97%
10g
$ 880.00

Acrotein
1-Boc-4-(4-chlorophenyl)-4-hydroxypiperidine 97%
5g
$ 550.00

ACHEMBLOCK
1-Boc-4-(4-chlorophenyl)-4-hydroxypiperidine 95%
5G
$ 405.00

Total 6 raw suppliers

Chemical Property of 1-N-BOC-4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDINE

Chemical Property:

PSA：49.77000
LogP:3.49640

Purity/Quality:

99% ^*data from raw suppliers

1-BOC-4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-N-BOC-4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDINE

There total 10 articles about 1-N-BOC-4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 39512-49-7
4-(4-chlorophenyl)-4-hydroxypiperidine

: 24424-99-5
di-tert-butyl dicarbonate

: 235109-63-4
4-(4-chloro-phenyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 18h; Inert atmosphere;
DOI:10.1002/chem.201903702

Reference yield: 78.0%

: 637-87-6
1-Chloro-4-iodobenzene

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 235109-63-4
4-(4-chloro-phenyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: 1-Chloro-4-iodobenzene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;

N-tert-butyloxycarbonylpiperidin-4-one; In tetrahydrofuran; at -78 ℃; for 1h; Inert atmosphere;

Reference yield: 74.0%

: 106-39-8
bromochlorobenzene

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 235109-63-4
4-(4-chloro-phenyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: bromochlorobenzene; N-tert-butyloxycarbonylpiperidin-4-one; With n-butyllithium; In tetrahydrofuran; hexanes; at -78 ℃;

With ammonium chloride; In tetrahydrofuran; hexanes; water;