2,2'-Azanediyldiphenol

Base Information

• Chemical Name: 2,2'-Azanediyldiphenol
• CAS No.: 2391-71-1
• Molecular Formula: C12H11NO2
• Molecular Weight: 201.225
• DSSTox Substance ID: DTXSID70542700
• Nikkaji Number: J1.289.428G
• Wikidata: Q82419439
• Mol file: 2391-71-1.mol

Synonyms:2,2'-Azanediyldiphenol;2391-71-1;2-[(2-hydroxyphenyl)amino]phenol;bis-(2-hydroxyphenyl)amine;SCHEMBL304891;DTXSID70542700;SB78098

Chemical Property of 2,2'-Azanediyldiphenol

Chemical Property:

• PSA: 52.49000
• LogP: 2.91440
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 201.078978594
• Heavy Atom Count: 15
• Complexity: 178

Purity/Quality:

99% ^*data from raw suppliers

2,2'-Azanediyldiphenol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)NC2=CC=CC=C2O)O

Technology Process of 2,2'-Azanediyldiphenol

There total 4 articles about 2,2'-Azanediyldiphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-Iodophenol (533-58-4) + 2-amino-phenol (95-55-6) → 2-(2-hydroxyphenlylamino)phenol (2391-71-1)

Guidance literature:

With potassium phosphate; copper(l) iodide; In N,N-dimethyl-formamide; at 80 ℃; for 16h; Inert atmosphere;

DOI:10.1002/ejoc.201001113

Reference yield: 61.0%

6-diazo-2-cyclohexen-1-one (928642-45-9) + 2-amino-phenol (95-55-6) → 2-(2-hydroxyphenlylamino)phenol (2391-71-1)

Guidance literature:

With oxygen; copper diacetate; In 1,4-dioxane; at 80 ℃; for 3h; Schlenk technique; Sealed tube;

DOI:10.1002/asia.201402080

Reference yield: 39.0%

2-amino-phenol (95-55-6) → phenoxazine (135-67-1) + 2-(2-hydroxyphenlylamino)phenol (2391-71-1)

Guidance literature:

With hydrogenchloride; at 240 ℃;

DOI:10.1016/S0040-4039(00)00203-3

upstream raw materials:

2-amino-phenol

2-Iodophenol

6-diazo-2-cyclohexen-1-one

Downstream raw materials:

(N-B)-phenyl{amino-2,2'-diphenolate-O,O',N}borane

9,10-Dioxa-4b-aza-9aλ⁵-phospha-indeno[1,2-a]inden-9a-ol; compound with dibenzyl-amine

Dibenzyl-(9,10-dioxa-4b-aza-9aλ⁵-phospha-indeno[1,2-a]inden-9a-yl)-amine

9a-Phenoxy-9,10-dioxa-4b-aza-9aλ⁵-phospha-indeno[1,2-a]indene