6-fluoro-3H-isobenzofuran-1-one

Base Information

Chemical Name:6-fluoro-3H-isobenzofuran-1-one
CAS No.:23932-84-5
Molecular Formula:C8H5FO2
Molecular Weight:152.125
Hs Code.:2932209090
DSSTox Substance ID:DTXSID00457515
Nikkaji Number:J856.308J
Wikidata:Q82280376
Mol file:23932-84-5.mol

Synonyms:23932-84-5;6-fluoro-3H-isobenzofuran-1-one;6-Fluoroisobenzofuran-1(3H)-one;6-fluoro-3H-2-benzofuran-1-one;6-fluoro-2-benzofuran-1(3H)-one;1(3H)-Isobenzofuranone, 6-fluoro-;6-fluoro-1,3-dihydro-2-benzofuran-1-one;6-Fluorophthalide;6-fluoro-1(3H)-isobenzofuranone;SCHEMBL856120;DTXSID00457515;LRPVIFOWOOZXEW-UHFFFAOYSA-N;YAA93284;MFCD11053086;AKOS005215808;DS-16050;AM20080857;CS-0035468;FT-0652747;EN300-235055;Y10487;A816995;F2196-0065;Z1198309551

Suppliers and Price of 6-fluoro-3H-isobenzofuran-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-fluoro-3H-2-benzofuran-1-one
50mg
$ 90.00

SynQuest Laboratories
6-Fluorophthalide 95.0%
250 mg
$ 200.00

SynChem
6-Fluoro-3H-isobenzofuran-1-one 95%
500 mg
$ 315.00

SynChem
6-Fluoro-3H-isobenzofuran-1-one 95%
1 g
$ 550.00

Matrix Scientific
6-Fluoroisobenzofuran-1(3H)-one 95+%
1g
$ 840.00

Matrix Scientific
6-Fluoroisobenzofuran-1(3H)-one 95+%
250mg
$ 378.00

Crysdot
6-Fluoroisobenzofuran-1(3H)-one 95+%
250mg
$ 316.00

Crysdot
6-Fluoroisobenzofuran-1(3H)-one 95+%
1g
$ 790.00

Chemenu
6-Fluoroisobenzofuran-1(3H)-one 95%
1g
$ 746.00

Apolloscientific
6-Fluorophthalide 95+%
250mg
$ 125.00

Total 19 raw suppliers

Chemical Property of 6-fluoro-3H-isobenzofuran-1-one

Chemical Property:

Melting Point:111.5-112 °C
Boiling Point:306.6±42.0 °C(Predicted)
PSA：26.30000
Density:1.379±0.06 g/cm3(Predicted)
LogP:1.49610
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:0.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:152.02735756
Heavy Atom Count:11
Complexity:181

Purity/Quality:

99%, ^*data from raw suppliers

6-fluoro-3H-2-benzofuran-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=C(C=C(C=C2)F)C(=O)O1

Technology Process of 6-fluoro-3H-isobenzofuran-1-one

There total 17 articles about 6-fluoro-3H-isobenzofuran-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 138786-65-9
methyl 2-(bromomethyl)-5-fluorobenzoate

: 23932-84-5
6-fluoroisobenzofuran-1(3H)-one

Guidance literature:: With calcium carbonate; In 1,4-dioxane; water; for 2.5h; Reflux;

Reference yield: 77.0%

: 229027-89-8
(2-bromo-4-fluorophenyl)methanol

: 23932-84-5
6-fluoroisobenzofuran-1(3H)-one

Guidance literature:: With dmap; 1,1'-bis-(diphenylphosphino)ferrocene; N-ethyl-N,N-diisopropylamine; palladium diacetate; In 1,4-dioxane; at 180 ℃; for 0.5h; microwave irradiation;
DOI:10.1016/j.tetlet.2004.04.110

Reference yield: 77.0%

: 124-38-9,18923-20-1
carbon dioxide

: 6-fluoro-1,1-diisopropyl-1,3-dihydrobenzo[c][1,2]oxasilole

: 23932-84-5
6-fluoroisobenzofuran-1(3H)-one

Guidance literature:: carbon dioxide; 6-fluoro-1,1-diisopropyl-1,3-dihydrobenzo[c][1,2]oxasilole; With copper(l) iodide; cesium fluoride; In dimethyl sulfoxide; at 60 ℃; for 24h; Glovebox;

With hydrogenchloride; In water; dimethyl sulfoxide; at 20 ℃; for 12h;
DOI:10.1039/c7gc00917h