2-hydroxy-N-(2-hydroxyethyl)-4-methylbenzamide

Base Information

Chemical Name:2-hydroxy-N-(2-hydroxyethyl)-4-methylbenzamide
CAS No.:24207-39-4
Molecular Formula:C₁₀H₁₃NO₃
Molecular Weight:195.218
Hs Code.:
DSSTox Substance ID:DTXSID801245803

Synonyms:24207-39-4;SCHEMBL8980662;DTXSID801245803;AKOS008975774;2-hydroxy-N-(2-hydroxyethyl)-4-methylbenzamide

Suppliers and Price of 2-hydroxy-N-(2-hydroxyethyl)-4-methylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-hydroxy-N-(2-hydroxyethyl)-4-methylbenzamide

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:195.08954328
Heavy Atom Count:14
Complexity:196

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)C(=O)NCCO)O

Technology Process of 2-hydroxy-N-(2-hydroxyethyl)-4-methylbenzamide

There total 2 articles about 2-hydroxy-N-(2-hydroxyethyl)-4-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4670-56-8
methyl 2-hydroxy-4-methylbenzoate

: 141-43-5
ethanolamine

: 24207-39-4
2-hydroxy-4-methyl-benzoic acid-(2-hydroxy-ethylamide)

Guidance literature:: at 170 ℃;
DOI:10.1021/jm00001a018

Reference yield:

: 24207-39-4
2-hydroxy-4-methyl-benzoic acid-(2-hydroxy-ethylamide)

Guidance literature:: entspr. Carbonsaeure, H2NCH2CH2OH;

Reference yield:

: 24207-39-4
2-hydroxy-4-methyl-benzoic acid-(2-hydroxy-ethylamide)

: 2,3-dihydro-7-methyl-3-(2'-nitrooxyethyl)-4H-1,3-benzoxazin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) p-toluenesulfonic acid, 2.) 3N aq. HCl / 1.) toluene, 2 h, reflux, 2.) THF, 24 h, reflux

2: thionyl chloride / CHCl₃ / 3 h / Heating

3: silver nitrate / acetonitrile / 2 h / Heating

With hydrogenchloride; thionyl chloride; toluene-4-sulfonic acid; silver nitrate; In chloroform; acetonitrile;
DOI:10.1021/jm00001a018