2-[5-(4-Chlorophenyl)thiophen-2-yl]acetamide

Base Information

Chemical Name:2-[5-(4-Chlorophenyl)thiophen-2-yl]acetamide
CAS No.:24675-44-3
Molecular Formula:C12H10ClNOS
Molecular Weight:251.737
Hs Code.:
DSSTox Substance ID:DTXSID90515719
Wikidata:Q82376762
Mol file:24675-44-3.mol

Synonyms:24675-44-3;2-[5-(4-Chlorophenyl)thiophen-2-yl]acetamide;SCHEMBL3306078;DTXSID90515719;FT-0735280

Suppliers and Price of 2-[5-(4-Chlorophenyl)thiophen-2-yl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[5-(4-Chlorophenyl)thiophen-2-yl]acetamide

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:251.0171628
Heavy Atom Count:16
Complexity:253

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CC=C(S2)CC(=O)N)Cl

Technology Process of 2-[5-(4-Chlorophenyl)thiophen-2-yl]acetamide

There total 3 articles about 2-[5-(4-Chlorophenyl)thiophen-2-yl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 84863-77-4
[5-(4-Chloro-phenyl)-thiophen-2-yl]-acetic acid methyl ester

: 24675-44-3
2-[5-(4-Chloro-phenyl)-thiophen-2-yl]-acetamide

Guidance literature:: With ammonia; In methanol; for 96h; Ambient temperature;
DOI:10.1021/jm00359a015

Reference yield:

: 51335-90-1
1-[5-(4-chlorophenyl)thiophen-2-yl]ethan-1-one

: 24675-44-3
2-[5-(4-Chloro-phenyl)-thiophen-2-yl]-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 70percent HClO₄, Tl(NO₃)3 / Ambient temperature

2: 95 percent / NH₃ / methanol / 96 h / Ambient temperature

With perchloric acid; ammonia; thallium(III) nitrate; In methanol;
DOI:10.1021/jm00359a015