3-Chloro-4-phenylfurazan

Base Information

• Chemical Name: 3-Chloro-4-phenylfurazan
• CAS No.: 24786-13-8
• Molecular Formula: C₈H₅ClN₂O
• Molecular Weight: 180.593
• DSSTox Substance ID: DTXSID10524585
• Nikkaji Number: J507.985C
• Wikidata: Q82391555
• Mol file: 24786-13-8.mol

Synonyms:3-CHLORO-4-PHENYLFURAZAN;24786-13-8;3-chloro-4-phenyl-1,2,5-oxadiazole;DTXSID10524585;AKOS006372494;3-chloro-4-phenyl-[1,2,5]oxadiazole

Chemical Property of 3-Chloro-4-phenylfurazan

Chemical Property:

• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 180.0090405
• Heavy Atom Count: 12
• Complexity: 150

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NON=C2Cl

Technology Process of 3-Chloro-4-phenylfurazan

There total 4 articles about 3-Chloro-4-phenylfurazan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4-Chloro-3-phenylfuroxan (82775-80-2) → 3-Chloro-4-phenylfurazan (24786-13-8)

Guidance literature:

With phosphorous acid trimethyl ester; for 4h; Heating;

Reference yield:

2-hydroxyimino-2-phenyl-acetohydroximoyl chloride (10242-38-3) → 3-Chloro-4-phenylfurazan (24786-13-8)

Guidance literature:

With phosphorus pentachloride;

Reference yield:

3-Chloro-4-phenylfuroxan (82775-81-3) → 3-Chloro-4-phenylfurazan (24786-13-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 °C / Isomerisation

2: 80 percent / Trimethyl phosphite / 4 h / Heating

With phosphorous acid trimethyl ester;

upstream raw materials:

2-hydroxyimino-2-phenyl-acetohydroximoyl chloride

4-Chloro-3-phenylfuroxan

diethyl ether

phosphorus pentachloride

Downstream raw materials:

3-methoxy-4-phenyl-furazan

3-ethoxy-4-phenylfurazan

3-hydroxy-4-phenylfurazan

4-phenyl-[1,2,5]oxadiazol-3-one