Phenyl(5,6,7,8-tetrahydronaphthalen-2-yl) ketone

Base Information

• Chemical Name: Phenyl(5,6,7,8-tetrahydronaphthalen-2-yl) ketone
• CAS No.: 2657-20-7
• Molecular Formula: C17H16 O
• Molecular Weight: 236.313
• Hs Code.: 2914399090
• Mol file: 2657-20-7.mol

Synonyms:Ketone,phenyl 5,6,7,8-tetrahydro-2-naphthyl (7CI,8CI); NSC 5539

Chemical Property of Phenyl(5,6,7,8-tetrahydronaphthalen-2-yl) ketone

Chemical Property:

• Vapor Pressure: 2E-06mmHg at 25°C
• Boiling Point: 394.3°Cat760mmHg
• Flash Point: 173°C
• PSA: 17.07000
• Density: 1.102g/cm³
• LogP: 3.79640

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenyl(5,6,7,8-tetrahydronaphthalen-2-yl) ketone

There total 6 articles about Phenyl(5,6,7,8-tetrahydronaphthalen-2-yl) ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tetralin (119-64-2) + benzoic acid (65-85-0,8013-63-6) → phenyl(5,6,7,8-tetrahydronaphthalen-2-yl)methanone (2657-20-7) + phenyl(5,6,7,8-tetrahydronaphthalen-1-yl)methanone (35310-83-9)

Guidance literature:

With trifluoroacetic acid; trifluoroacetic anhydride; at 20 ℃; for 12h; Overall yield = 72 %; Overall yield = 127 mg; Inert atmosphere; Microwave irradiation;

DOI:10.1016/j.tetlet.2018.01.026

Reference yield:

tetralin (119-64-2) + benzoyl chloride (98-88-4) → phenyl(5,6,7,8-tetrahydronaphthalen-2-yl)methanone (2657-20-7)

Guidance literature:

With aluminium trichloride; nitrobenzene;

DOI:10.1021/ja01171a519

Reference yield:

5,6,7,8-tetrahydronaphthalene-2-carbonyl chloride (91586-31-1) → phenyl(5,6,7,8-tetrahydronaphthalen-2-yl)methanone (2657-20-7)

Guidance literature:

With aluminium trichloride; benzene;

upstream raw materials:

5,6,7,8-tetrahydronaphthalene-2-carbonyl chloride

tetralin

benzoyl chloride

benzoic acid

Downstream raw materials:

C₆H₅COC₁₀H₇

2,3-benzofluorene

benzo[c]fluorene

2-benzylnaphthalene