Lithium 2,5-difluorobenzen-1-ide

Base Information

Chemical Name:Lithium 2,5-difluorobenzen-1-ide
CAS No.:25152-36-7
Molecular Formula:C6H3F2Li
Molecular Weight:120.028
Hs Code.:
DSSTox Substance ID:DTXSID60544359
Mol file:25152-36-7.mol

Synonyms:Lithium 2,5-difluorobenzen-1-ide;25152-36-7;SCHEMBL2458022;DTXSID60544359

Suppliers and Price of Lithium 2,5-difluorobenzen-1-ide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Lithium 2,5-difluorobenzen-1-ide

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:120.03628485
Heavy Atom Count:9
Complexity:180

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:[Li+].C1=CC(=[C-]C=C1F)F

Technology Process of Lithium 2,5-difluorobenzen-1-ide

There total 1 articles about Lithium 2,5-difluorobenzen-1-ide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 540-36-3
para-difluorobenzene

: 25152-36-7
C₆H₃F₂Li

Guidance literature:: With lithium chloride; lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; Reagent/catalyst; Kinetics;
DOI:10.1021/jo802713y

Reference yield:

: 25152-36-7
C₆H₃F₂Li

: 4883-70-9
3-(4-oxocyclohexyl)propanoic acid

: cis-3-[4-(2,5-difluorophenvl)-4-hydroxycyclohexyl]propanoic acid

: trans-3-[4-(2,5-difluorophenvl)-4-hydroxycyclohexyl]propanoic acid

Guidance literature:: 3-(4-oxocyclohexyl)propanoic acid; With isopropylmagnesium chloride; In tetrahydrofuran; at -65 - -10 ℃; for 0.5h;

C₆H₃F₂Li; In tetrahydrofuran; at -60 - -10 ℃;

With acetic acid; In tetrahydrofuran; at 0 - 20 ℃;