Hexanoic acid, 6-[[1-oxo-6-[[(phenylmethoxy)carbonyl]amino]hexyl]amino]-, methyl ester

Base Information

Chemical Name:Hexanoic acid, 6-[[1-oxo-6-[[(phenylmethoxy)carbonyl]amino]hexyl]amino]-, methyl ester
CAS No.:25580-88-5
Molecular Formula:C21H32N2O5
Molecular Weight:392.495
Hs Code.:
Mol file:25580-88-5.mol

Synonyms:Cbz-εAhx-εAhx-OMe;N-(6-Benzyloxycarbonylamino-hexanoyl)-6-amino-capronsaeure-methylester;

Suppliers and Price of Hexanoic acid, 6-[[1-oxo-6-[[(phenylmethoxy)carbonyl]amino]hexyl]amino]-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-[6-(Carboxyamino)hexanamido]-hexanoicAcidN-BenzylMethylEster
10g
$ 880.00

TRC
6-[6-(Carboxyamino)hexanamido]-hexanoicAcidN-BenzylMethylEster
5g
$ 485.00

TRC
6-[6-(Carboxyamino)hexanamido]-hexanoicAcidN-BenzylMethylEster
2.5g
$ 255.00

TRC
6-[6-(Carboxyamino)hexanamido]-hexanoicAcidN-BenzylMethylEster
1g
$ 110.00

TRC
6-[6-(Carboxyamino)hexanamido]-hexanoicAcidN-BenzylMethylEster
500mg
$ 65.00

Total 0 raw suppliers

Chemical Property of Hexanoic acid, 6-[[1-oxo-6-[[(phenylmethoxy)carbonyl]amino]hexyl]amino]-, methyl ester

Chemical Property:

PSA：93.73000
LogP:4.10460

Purity/Quality:: 6-[6-(Carboxyamino)hexanamido]-hexanoicAcidN-BenzylMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 6-[6-(Carboxyamino)hexanamido]-hexanoic Acid N-Benzyl Methyl Ester is an intermediate in the synthesis of 6-(6-(6-Aminohexanamido)hexanamido)hexanoic Acid (A618823). 6-(6-(6-Aminohexanamido)hexanamido)hexanoic Acid is used in the making of a preconjugate which serves as immunoreactive conjugate useful as a developer antigen in a competitive inhibition immunoassay for the polymorphic analyte. Also used in the efficient synthesis of a heterobifunctional coupling agent.

Technology Process of Hexanoic acid, 6-[[1-oxo-6-[[(phenylmethoxy)carbonyl]amino]hexyl]amino]-, methyl ester

There total 6 articles about Hexanoic acid, 6-[[1-oxo-6-[[(phenylmethoxy)carbonyl]amino]hexyl]amino]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 67-56-1
methanol

: 49701-55-5
13-benzyloxycarbonylamino-8-oxo-7-azatridecanoic acid

: 25580-88-5
methyl 13-benzyloxycarbonylamino-8-oxo-7-azatridecanoate

Guidance literature:: With toluene-4-sulfonic acid; In dichloromethane; for 15h; Heating;
DOI:10.1007/BF00473947

Reference yield:

: 1947-00-8
6-(benzyloxycarbonylamino)hexanoic acid

: 25580-88-5
methyl 13-benzyloxycarbonylamino-8-oxo-7-azatridecanoate

Guidance literature:: Multi-step reaction with 3 steps

1: DCC / dioxane / 24 h / 0 °C

2: aq. NaHCO₃ / 1,2-dimethoxy-ethane / 5 h / 20 °C

3: 92 percent / p-TsOH / CH₂Cl₂ / 15 h / Heating

With sodium hydrogencarbonate; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; In 1,4-dioxane; 1,2-dimethoxyethane; dichloromethane;
DOI:10.1007/BF00473947

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 25580-88-5
methyl 13-benzyloxycarbonylamino-8-oxo-7-azatridecanoate

Guidance literature:: Multi-step reaction with 4 steps

1: 83 percent / 4 M NaOH / 4 h / 0 - 20 °C

2: DCC / dioxane / 24 h / 0 °C

3: aq. NaHCO₃ / 1,2-dimethoxy-ethane / 5 h / 20 °C

4: 92 percent / p-TsOH / CH₂Cl₂ / 15 h / Heating

With sodium hydroxide; sodium hydrogencarbonate; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; In 1,4-dioxane; 1,2-dimethoxyethane; dichloromethane;
DOI:10.1007/BF00473947