(4-aminophenyl)(2-thienyl)methanone

Base Information

• Chemical Name: (4-aminophenyl)(2-thienyl)methanone
• CAS No.: 25706-30-3
• Molecular Formula: C11H9NOS
• Molecular Weight: 203.26000
• Mol file: 25706-30-3.mol

Synonyms:2-(p-Amino-benzoyl)-thiophen;(4-amino-phenyl)-[2]thienyl ketone;(4-Amino-phenyl)-[2]thienyl-keton;(4-Amino-phenyl)-thiophen-2-yl-methanone;

Chemical Property of (4-aminophenyl)(2-thienyl)methanone

Chemical Property:

• Melting Point: 118 - 120 °C
• Boiling Point: 390.0±22.0 °C(Predicted)
• PKA: 1.50±0.10(Predicted)
• PSA: 71.33000
• Density: 1.275±0.06 g/cm3(Predicted)
• LogP: 3.14250

Purity/Quality:

98%min ^*data from raw suppliers

(4-aminophenyl)(2-thienyl)methanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-aminophenyl)(2-thienyl)methanone

There total 5 articles about (4-aminophenyl)(2-thienyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4-nitro-phenyl)-thiophen-2-yl-methanone (34715-92-9) → 2-(4-Aminobenzoyl)thiophene (25706-30-3)

Guidance literature:

With tin(ll) chloride; In ethanol; for 3h; Heating / reflux;

Reference yield:

2-(4-chlorobenzoyl)thiophene (4153-45-1) → 2-(4-Aminobenzoyl)thiophene (25706-30-3)

Guidance literature:

With ammonium hydroxide; copper(II) sulfate; at 215 ℃;

Reference yield:

(4-bromophenyl)(thien-2-yl)methanone (4160-65-0) → 2-(4-Aminobenzoyl)thiophene (25706-30-3)

Guidance literature:

With copper(I) oxide; ammonium hydroxide; copper; at 200 ℃;

upstream raw materials:

2-(4-chlorobenzoyl)thiophene

(4-bromophenyl)(thien-2-yl)methanone

4-chloro-benzoyl chloride

(4-nitro-phenyl)-thiophen-2-yl-methanone

Downstream raw materials:

[4-(N'-methyl-thioureido)-phenyl]-[2]thienyl ketone

(4-Pyrrol-1-yl-phenyl)-thiophen-2-yl-methanone

1-[(4-Pyrrol-1-yl-phenyl)-thiophen-2-yl-methyl]-1H-imidazole

(4-Pyrrol-1-yl-phenyl)-thiophen-2-yl-methanol

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