2-(DediMethyldeaMino)deethyl Denaverine

Base Information

• Chemical Name: 2-(DediMethyldeaMino)deethyl Denaverine
• CAS No.: 2594-45-8
• Molecular Formula: C20H24O3
• Molecular Weight: 312.409
• Mol file: 2594-45-8.mol

Synonyms:(2-Ethyl-butoxy)-diphenyl-acetic acid;α-<2-Aethyl-butyloxy>-benzilsaeure;2-(Dedimethyldeamino)deethyl Denaverine;α-(2-Aethyl-butyloxy)-benzilsaeure;

Chemical Property of 2-(DediMethyldeaMino)deethyl Denaverine

Chemical Property:

• Melting Point: 104-106 °C
• Boiling Point: 436.7±40.0 °C(Predicted)
• PKA: 3.05±0.10(Predicted)
• PSA: 46.53000
• Density: 1.090±0.06 g/cm3(Predicted)
• LogP: 4.46760

Purity/Quality:

95% ^*data from raw suppliers

2-(Dedimethyldeamino)deethylDenaverine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Metabolite of Denaverine.

Technology Process of 2-(DediMethyldeaMino)deethyl Denaverine

There total 6 articles about 2-(DediMethyldeaMino)deethyl Denaverine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Denaverine hydrochloride (3321-06-0) → 2,2-diphenylacetic acid (117-34-0) + Diphenylessigsaeure(2-dimethylaminoethyl)ester (2618-50-0) + 2-(dimethylamino)ethyl phenylglycolate (968-46-7) + 2-(2-Ethylbutoxy)-2,2-diphenylessigsaeure (2594-45-8) + Benzilic acid (76-93-7)

Guidance literature:

With hydrogenchloride; In water; Heating; hydrolysis; other reaction partner NaOH, other temperatures from room temp. to reflux, time from 10 min to 300 d;

Reference yield:

2-ethyl-1-butanol (97-95-0) + C14H11ClO3 → 2-(2-Ethylbutoxy)-2,2-diphenylessigsaeure (2594-45-8)

Guidance literature:

With potassium carbonate; at 25 - 100 ℃; for 20h; Reagent/catalyst; Temperature; Large scale;

Reference yield:

Benzilic acid (76-93-7) → 2-(2-Ethylbutoxy)-2,2-diphenylessigsaeure (2594-45-8)

Guidance literature:

Multi-step reaction with 2 steps

1: acetyl chloride / acetonitrile / 20 h / 25 °C / Large scale

2: potassium carbonate / 20 h / 25 - 100 °C / Large scale

With potassium carbonate; acetyl chloride; In acetonitrile;

upstream raw materials:

Denaverine hydrochloride

2-ethyl-1-butanol

Benzilic acid

Downstream raw materials:

2-(2-Ethylbutoxy)diphenylessigsauremethylester

denaverine hydrochloride

Refernces

• 1、 Smolinka, Kai,G?ber, Berthold. "Biomimetic oxidation of denaverine hydrochloride". . p. 679 - 683. Retrieved 2007/10/03.