2-Propenoic acid, 2-cyano-3-(1H-indol-3-yl)-

Base Information

Chemical Name:2-Propenoic acid, 2-cyano-3-(1H-indol-3-yl)-
CAS No.:26272-42-4
Molecular Formula:C₁₂H₈N₂O₂
Molecular Weight:212.208
Hs Code.:

Synonyms:2-cyano-3-indol-3-yl-acrylic acid;2-Propenoic acid,2-cyano-3-(1H-indol-3-yl);2-Cyan-3-indol-3-yl-acrylsaeure;2-cyano-3-(3-indolyl)acrylic acid;2-Cyan-3-(3-indolyl)-acrylsaeure;(2Z)-2-cyano-3-(1H-indol-3-yl)prop-2-erioic acid;

Suppliers and Price of 2-Propenoic acid, 2-cyano-3-(1H-indol-3-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
2-cyano-3-(1H-indol-3-yl)-2-Propenoicacid 97.00%
1G
$ 1940.00

Total 0 raw suppliers

Chemical Property of 2-Propenoic acid, 2-cyano-3-(1H-indol-3-yl)-

Chemical Property:

PSA：76.88000
LogP:2.15948

Purity/Quality:: 2-cyano-3-(1H-indol-3-yl)-2-Propenoicacid 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Propenoic acid, 2-cyano-3-(1H-indol-3-yl)-

There total 6 articles about 2-Propenoic acid, 2-cyano-3-(1H-indol-3-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 372-09-8
cyanoacetic acid

: 75629-45-7
(Z)-3-(pyrrolidin-1-ylmethylene)-3H-indole

: 26272-42-4
2-cyano-3-(3-indolyl)acrylic acid

Guidance literature:: In pyridine; at 25 ℃; for 5h; var.: solv.: EtOH;

Reference yield:

: 1453484-20-2
tert-butyl 3-[(1Z)-2-cyano-3-ethoxy-3-oxoprop-1-en-1-yl]-1H-indole-1-carboxylate

: 26272-42-4
2-cyano-3-(3-indolyl)acrylic acid

Guidance literature:: With water; sodium hydroxide; In ethanol; at 20 ℃; for 3h;

Reference yield:

: 57476-50-3
1-tert-butoxycarbonyl-3-formylindole

: 26272-42-4
2-cyano-3-(3-indolyl)acrylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / isopropyl alcohol / 1 h / 0 °C

2: sodium hydroxide; water / ethanol / 3 h / 20 °C

With water; potassium hydroxide; sodium hydroxide; In ethanol; isopropyl alcohol;