34DIMETHOXY2METHYLBUTYROPHENONE

Base Information

• Chemical Name: 34DIMETHOXY2METHYLBUTYROPHENONE
• CAS No.: 67049-70-1
• Molecular Formula: C₁₃H₁₈O₃
• Molecular Weight: 222.284
• Mol file: 67049-70-1.mol

Synonyms:3,4-dimethoxy-2-hydroxybenzaldehyde oxime;3',4'-Dimethoxy-2-methyl-butyrophenon;Benzaldehyde,2-hydroxy-3,4-dimethoxy-,oxime;

Chemical Property of 34DIMETHOXY2METHYLBUTYROPHENONE

Chemical Property:

• Vapor Pressure: 0.000313mmHg at 25°C
• Boiling Point: 320.7°Cat760mmHg
• Flash Point: 138.8°C
• PSA: 35.53000
• Density: 1.015g/cm³
• LogP: 2.93260

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 34DIMETHOXY2METHYLBUTYROPHENONE

There total 4 articles about 34DIMETHOXY2METHYLBUTYROPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sec.-butyllithium (598-30-1) + Veratric acid (93-07-2) → 3',4'-Dimethoxy-2-methyl-butyrophenon (67049-70-1)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; methyl iodide; In tetrahydrofuran; hexane; cyclohexane; at -30 - 20 ℃;

DOI:10.1016/j.tet.2008.08.086

Reference yield:

1,2-dimethoxybenzene (91-16-7) + iso-butyl chloroformate (5856-79-1,57526-28-0) → 3',4'-Dimethoxy-2-methyl-butyrophenon (67049-70-1)

Guidance literature:

With aluminium trichloride; In benzene;

DOI:10.1021/jm00332a013

Reference yield:

sec.-butyllithium (598-30-1) + Veratric acid (93-07-2) + methyl iodide (74-88-4) → 4,5-dimethoxy-2-methylbenzoic acid (20736-28-1,131035-49-9) + 3',4'-Dimethoxy-2-methyl-butyrophenon (67049-70-1) + 2-methyl-3,4-dimethoxybenzoic acid (5722-94-1) + 3-methyl-4,5-dimethoxybenzoic acid (80547-77-9)

Guidance literature:

sec.-butyllithium; Veratric acid; With N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; hexane; cyclohexane; at -78 - -30 ℃; for 2h;

methyl iodide; In tetrahydrofuran; hexane; cyclohexane; at -30 - 20 ℃; Further stages.;

DOI:10.1016/j.tet.2008.08.086

upstream raw materials:

1,2-dimethoxybenzene

iso-butyl chloroformate

2-Methylbutanoic acid

sec.-butyllithium

Downstream raw materials:

1,2-dimethoxy-4-(2-methyl-butyl)-benzene

4-(2-methyl-butyl)-benzene-1,2-diol

3',4'-Dihydroxy-2-methyl-butyrophenon

Refernces

• 1、 Kraft, Philip,Eichenberger, Walter. "Conception, characterization and correlation of new marine odorants". . p. 3735 - 3743. Retrieved 2007/10/03.