2-Hydroxy-3,4-dimethylbenzaldehyde

Base Information

Chemical Name:2-Hydroxy-3,4-dimethylbenzaldehyde
CAS No.:26429-02-7
Molecular Formula:C9H10O2
Molecular Weight:150.177
Hs Code.:
DSSTox Substance ID:DTXSID80428344
Wikidata:Q82241174
Mol file:26429-02-7.mol

Synonyms:2-hydroxy-3,4-dimethylbenzaldehyde;26429-02-7;Benzaldehyde, 2-hydroxy-3,4-dimethyl-;2-Hydroxy-3,4-dimethyl-benzaldehyde;SCHEMBL3065272;DTXSID80428344;3,4-Dimethyl-2-hydroxybenzaldehyde;BBA42902;AKOS002683657;WS-02059;D85771;EN300-365469;Z1198170007

Suppliers and Price of 2-Hydroxy-3,4-dimethylbenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

CHESS?
AD060068:2-Hydroxy-3,4-dimethyl-benzaldehyde 95
1 g
$ 336.00

Alichem
3,4-Dimethyl-2-hydroxybenzaldehyde
1g
$ 1564.50

Alichem
3,4-Dimethyl-2-hydroxybenzaldehyde
500mg
$ 815.00

Alichem
3,4-Dimethyl-2-hydroxybenzaldehyde
250mg
$ 480.00

Total 8 raw suppliers

Chemical Property of 2-Hydroxy-3,4-dimethylbenzaldehyde

Chemical Property:

PSA：37.30000
LogP:1.82150
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:150.068079557
Heavy Atom Count:11
Complexity:145

Purity/Quality:

HPLC≥98% ^*data from raw suppliers

AD060068:2-Hydroxy-3,4-dimethyl-benzaldehyde 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=C(C=C1)C=O)O)C

Technology Process of 2-Hydroxy-3,4-dimethylbenzaldehyde

There total 6 articles about 2-Hydroxy-3,4-dimethylbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 526-75-0
2,3-Dimethylphenol

: 26429-02-7
2-hydroxy-3,4-dimethylbenzaldehyde

Guidance literature:: 2,3-Dimethylphenol; With magnesium methanolate; at 20 ℃; for 0.0166667h;

formaldehyd; at 20 ℃; for 0.166667h;

With sulfuric acid; at 20 ℃; for 0.166667h; regioselective reaction;
DOI:10.13005/ojc/290445

Reference yield: 28.0%

: 4885-02-3
Dichloromethyl methyl ether

: 526-75-0
2,3-Dimethylphenol

: 58380-40-8
2,3-Dimethyl-4-hydroxybenzaldehyde

: 26429-02-7
2-hydroxy-3,4-dimethylbenzaldehyde

Guidance literature:: 2,3-Dimethylphenol; With aluminum (III) chloride; In dichloromethane; at 20 ℃; for 0.166667h; Inert atmosphere;

Dichloromethyl methyl ether; In dichloromethane; at 20 ℃; for 0.166667h; Overall yield = 44 %; Inert atmosphere;
DOI:10.1055/s-0033-1340302

Reference yield:

: 526-75-0
2,3-Dimethylphenol

: 26429-02-7
2-hydroxy-3,4-dimethylbenzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 3 h / 0 - 20 °C / Inert atmosphere

2.1: n-butyllithium / hexane; diethyl ether / 3 h / 0 - 20 °C / Inert atmosphere

2.2: 0.17 h / 0 °C / Inert atmosphere

2.3: Inert atmosphere

3.1: montmorillonite K-10 / benzene / 24 h / Reflux

With n-butyllithium; sodium hydride; In diethyl ether; hexane; N,N-dimethyl-formamide; mineral oil; benzene;
DOI:10.1021/ja311902f