9H-Fluorene-9,9-dimethanol

Base Information

• Chemical Name: 9H-Fluorene-9,9-dimethanol
• CAS No.: 4425-93-8
• Molecular Formula: C15H14O2
• Molecular Weight: 226.275
• Hs Code.: 2906299090
• NSC Number: 402230
• DSSTox Substance ID: DTXSID50322885
• Nikkaji Number: J2.027.573A
• Wikidata: Q82081664
• Mol file: 4425-93-8.mol

Synonyms:9H-Fluorene-9,9-dimethanol;4425-93-8;[9-(hydroxymethyl)fluoren-9-yl]methanol;(9H-fluorene-9,9-diyl)dimethanol;9,9-bis(hydroxymethyl)fluorene;(9-Hydroxymethyl-9H-fluoren-9-yl)-methanol;NSC 402230;Fluorene-9,9-dimethanol;NSC402230;9,9-dihydroxymethylfluorene;9,9-di(hydroxymethyl)fluorene;SCHEMBL1069782;9,9-bis(hydroxymethyl)-fluorene;DTXSID50322885;C(O)C1(CO)c2ccccc2c3ccccc13;AMY18620;9H-Fluorene-9,9-dimethanol, 98%;MFCD01321348;AKOS015913468;NSC-402230;SB37204;DS-15155;C75196;A851672

Chemical Property of 9H-Fluorene-9,9-dimethanol

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 142-145oC(lit.)
• Boiling Point: 422.8°Cat760mmHg
• Flash Point: 207.4°C
• PSA: 40.46000
• Density: 1.23g/cm³
• LogP: 1.93770
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 226.099379685
• Heavy Atom Count: 17
• Complexity: 248

Purity/Quality:

99.9% ^*data from raw suppliers

9H-Fluorene-9,9-dimethanol 98% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3C2(CO)CO
• Uses: 9H-Fluorene-9,9-dimethanol may be used in the synthesis of:4,4′-(9H-fluorene-9-yl-dimethoxy)diphthalonitrile]poly- [oxy(9H-fluoren-9,9-dimethylene)oxy(tetramethyldisilylene)]9,9-(Ph2POCH2)2-fluorene, a diphosphinite ligand

Technology Process of 9H-Fluorene-9,9-dimethanol

There total 1 articles about 9H-Fluorene-9,9-dimethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 9H-fluorene (86-73-7) → (9H-fluorene-9,9-diyl)dimethanol (4425-93-8) + 9-Fluorenylmethanol (24324-17-2)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction. Yields of byproduct given; 1) THF, hexane, 0 deg C, 3 min, 2) 0 deg C to r.t., 25 min;

DOI:10.1055/s-1992-26232

Reference yield: 88.2%

(9H-fluorene-9,9-diyl)dimethanol (4425-93-8) + phenyldimethylsilyl chloride (768-33-2) → 9,9-bis((dimethyl-phenyl-silyl)oxymethyl)fluorene

Guidance literature:

(9H-fluorene-9,9-diyl)dimethanol; With triethylamine; In dichloromethane; at 0 ℃;

phenyldimethylsilyl chloride; at 0 ℃; for 2h;

Reference yield: 62.0%

(9H-fluorene-9,9-diyl)dimethanol (4425-93-8) + methyl iodide (74-88-4) → 9-methoxymethyl-9-hydroxymethyl-fluorene

Guidance literature:

(9H-fluorene-9,9-diyl)dimethanol; methyl iodide; In tetrahydrofuran;

With sodium hydride; at 20 ℃; for 4h;

upstream raw materials:

formaldehyd

9H-fluorene

Downstream raw materials:

2-(2-phenyl-spiro[[1,3]dioxane-5,9'-fluoren]-2-yl)-pyridine

C₂₂H₁₇NO₄

C₂₂H₁₈O₂

C₂₃H₂₀O₃

Refernces