2-Propenoic acid, 2-fluoro-3-(4-methoxyphenyl)-, (Z)-

Base Information

Chemical Name:2-Propenoic acid, 2-fluoro-3-(4-methoxyphenyl)-, (Z)-
CAS No.:26928-12-1
Molecular Formula:C10H9FO3
Molecular Weight:196.178
Hs Code.:

Synonyms:2-Propenoic acid,2-fluoro-3-(4-methoxyphenyl)-,(Z);2-fluoro-3-(4-methoxy-phenyl)-propenoic acid;(Z)-2-fluoro-3-(4-methoxyphenyl)-2-propenoic acid;

Suppliers and Price of 2-Propenoic acid, 2-fluoro-3-(4-methoxyphenyl)-, (Z)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Propenoic acid, 2-fluoro-3-(4-methoxyphenyl)-, (Z)-

Chemical Property:

Boiling Point:348.1±27.0 °C(Predicted)
PSA：46.53000
Density:1.271±0.06 g/cm3(Predicted)
LogP:2.09020

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Propenoic acid, 2-fluoro-3-(4-methoxyphenyl)-, (Z)-

There total 8 articles about 2-Propenoic acid, 2-fluoro-3-(4-methoxyphenyl)-, (Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 30094-32-7
(diethoxy phosphoryl) fluoroacetic acid

: 123-11-5
4-methoxy-benzaldehyde

: 598-02-7
Diethyl phosphate

: 26928-12-1
(Z)-2-fluoro-3-(4-methoxyphenyl)-2-propenoic acid

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; 1.) -78 deg C, 1 h; 2.) 15 h room temperature;
DOI:10.1016/0022-328X(87)85116-1

Reference yield: 86.0%

: 26927-88-8
(Z)-3-(4-methoxyphenyl)-2-fluoroacrylic acid ethyl ester

: 26928-12-1
(Z)-2-fluoro-3-(4-methoxyphenyl)-2-propenoic acid

Guidance literature:: With water; potassium hydroxide; In ethanol; for 18h; Reflux; Inert atmosphere;
DOI:10.1002/chem.201405119

Reference yield: 72.0%

: 1198794-78-3
C₁₀H₉ClF₄O₂

: 26928-12-1
(Z)-2-fluoro-3-(4-methoxyphenyl)-2-propenoic acid

Guidance literature:: C₁₀H₉ClF₄O₂; With n-butyllithium; In tetrahydrofuran; hexane; at -80 ℃; for 2h; Inert atmosphere;

With methanesulfonyl chloride; In tetrahydrofuran; hexane; at 0 ℃; for 1h; Inert atmosphere;

With N-benzyl-N,N,N-triethylammonium chloride; water; sodium hydroxide; In tetrahydrofuran; hexane; at 20 ℃; for 1h; stereospecific reaction; Inert atmosphere;
DOI:10.1002/chem.201100900