Methanone, 2-benzofuranyl(4-fluorophenyl)-

Base Information

Chemical Name:Methanone, 2-benzofuranyl(4-fluorophenyl)-
CAS No.:27044-77-5
Molecular Formula:C15H9FO2
Molecular Weight:240.234
Hs Code.:2932999099
DSSTox Substance ID:DTXSID70353898
Nikkaji Number:J3.005.115G
Wikidata:Q82131741
ChEMBL ID:CHEMBL1485375
Mol file:27044-77-5.mol

Synonyms:27044-77-5;2-(4-Fluorobenzoyl)benzofuran;MLS000111098;Methanone, 2-benzofuranyl(4-fluorophenyl)-;2-(4-fluorobenzoyl)-1-benzofuran;Cambridge id 6338175;Oprea1_241447;CHEMBL1485375;DTXSID70353898;HMS2404E05;AKOS001681575;CCG-116541;SMR000107025;EU-0017034;Z31308541

Suppliers and Price of Methanone, 2-benzofuranyl(4-fluorophenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(4-FLUOROBENZOYL)BENZOFURAN 95.00%
5MG
$ 496.58

Total 1 raw suppliers

Chemical Property of Methanone, 2-benzofuranyl(4-fluorophenyl)-

Chemical Property:

PSA：30.21000
LogP:3.80290
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:240.05865769
Heavy Atom Count:18
Complexity:310

Purity/Quality:: 2-(4-FLUOROBENZOYL)BENZOFURAN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=C(O2)C(=O)C3=CC=C(C=C3)F

Technology Process of Methanone, 2-benzofuranyl(4-fluorophenyl)-

There total 13 articles about Methanone, 2-benzofuranyl(4-fluorophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 27044-77-5
benzofuran-2-yl(4-fluorophenyl)methanone

Guidance literature:: With (phthalocyaninato)iron(II); potassium carbonate; In tetrahydrofuran; at 100 ℃; for 18h; Schlenk technique;

Reference yield: 73.0%

: 88284-48-4
2-(trimethylsilyl)phenyl trifluoromethanesulfonate

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 403-29-2
2-bromo-4'-fluoroacetophenone

: 27044-77-5
benzofuran-2-yl(4-fluorophenyl)methanone

Guidance literature:: With potassium fluoride; 18-crown-6 ether; potassium carbonate; at 60 ℃; for 6h;
DOI:10.1039/c8ob00631h

Reference yield: 64.0%

: 54008-77-4
2-bromo-1-benzofuran

: 459-57-4
4-fluorobenzaldehyde

: 27044-77-5
benzofuran-2-yl(4-fluorophenyl)methanone

Guidance literature:: 2-bromo-1-benzofuran; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; for 2h;

4-fluorobenzaldehyde; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 1h;

With iodine; potassium carbonate; In tert-butyl alcohol; for 12h; Reflux;
DOI:10.1016/j.tet.2011.12.023