Methylisopropyl ketone O-methyloxime

Base Information

• Chemical Name: Methylisopropyl ketone O-methyloxime
• CAS No.: 27685-13-8
• Molecular Formula: C6H13NO
• Molecular Weight: 115.17400
• Mol file: 27685-13-8.mol

Synonyms:3-methyl-butan-2-one O-methyl-oxime;3-Methylbutan-2-on-O-methyloxim;Isopropyl-methyl-keton-oxim-O-merenylether;3-Methylbutan-2-one O-methyloxime;

Chemical Property of Methylisopropyl ketone O-methyloxime

Chemical Property:

• PSA: 21.59000
• LogP: 1.66470

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methylisopropyl ketone O-methyloxime

There total 1 articles about Methylisopropyl ketone O-methyloxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methyl-butan-2-one (563-80-4) + N-methoxylamine hydrochloride (593-56-6) → 3-methyl-2-butanone O-methyl oxime (27685-13-8)

Guidance literature:

With pyridine;

DOI:10.1021/ja046831c

Reference yield: 80.0%

3-methyl-2-butanone O-methyl oxime (27685-13-8) + bis(4-bromophenyl)iodonium triflate (139139-81-4) → C11H13BrO

Guidance literature:

3-methyl-2-butanone O-methyl oxime; bis(4-bromophenyl)iodonium triflate; With palladium diacetate; silver carbonate; Trimethylacetic acid; In 1,2-dichloro-ethane; at 85 ℃; for 5h;

With hydrogenchloride; formaldehyd; In tetrahydrofuran; at 20 ℃; for 5h; regioselective reaction;

DOI:10.1039/c5sc03903g

Reference yield:

3-methyl-2-butanone O-methyl oxime (27685-13-8) + 4-methylphenyl(mesityl)iodonium trifluoromethanesulfonate → C13H19NO + 3-methyl-4-p-tolylbutan-2-one O-methyl oxime

Guidance literature:

With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; silver(I) triflimide; Trimethylacetic acid; In cyclohexane; at 100 ℃; for 12h; Overall yield = 56 %; Overall yield = 23 mg; Schlenk technique; Molecular sieve; Inert atmosphere;

DOI:10.1021/jacs.5b06758

upstream raw materials:

3-methyl-butan-2-one

N-methoxylamine hydrochloride