Benzoic acid, 2-(methoxymethoxy)-3-methyl-

Base Information

• Chemical Name: Benzoic acid, 2-(methoxymethoxy)-3-methyl-
• CAS No.: 27701-27-5
• Molecular Formula: C10H12O4
• Molecular Weight: 196.203
• Mol file: 27701-27-5.mol

Synonyms:

Chemical Property of Benzoic acid, 2-(methoxymethoxy)-3-methyl-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 2-(methoxymethoxy)-3-methyl-

There total 3 articles about Benzoic acid, 2-(methoxymethoxy)-3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ortho-cresol (95-48-7,77504-84-8) → 2-Methoxymethoxy-3-methylbenzoesaeure (27701-27-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 79 percent / p-toluenesulfonic acid, 4A molecular sieves / CH₂Cl₂ / 72 h / Heating

2: 1.) TMEDA, n-BuLi / 1.) Et₂O, from -30 deg C to -5 deg C, 4 h, 2.) Et₂O, RT, overnight

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; 4 A molecular sieve; toluene-4-sulfonic acid; In dichloromethane;

DOI:10.1080/00397919308018594

Reference yield:

carbon dioxide (124-38-9,18923-20-1) + 1-methoxymethoxy-2-methylbenzene (55359-65-4) → 2-Methoxymethoxy-3-methylbenzoesaeure (27701-27-5)

Guidance literature:

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; Multistep reaction; 1.) Et₂O, from -30 deg C to -5 deg C, 4 h, 2.) Et₂O, RT, overnight;

DOI:10.1080/00397919308018594

Reference yield:

→ 2-Methoxymethoxy-3-methylbenzoesaeure (27701-27-5)

Guidance literature:

Ester, KOH ( nicht isoliert );

DOI:10.1021/ja00711a035

upstream raw materials:

carbon dioxide

1-methoxymethoxy-2-methylbenzene

ortho-cresol

Downstream raw materials:

3-methylsalicylic acid