Technology Process of Benzamide, 4-nitro-N-(4-oxobutyl)-
There total 4 articles about Benzamide, 4-nitro-N-(4-oxobutyl)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
carbonylhydridetris(triphenylphosphine)rhodium(I); hydrogen; sodium hydrogensulfite; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene;
In
water;
at 70 ℃;
for 1h;
under 6750.68 Torr;
regioselective reaction;
Inert atmosphere;
Microwave irradiation;
DOI:10.1002/cctc.202100181
- Guidance literature:
-
Multi-step reaction with 3 steps
1: thionyl chloride / 2 h / Reflux
2: triethylamine / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere
3: hydrogen; sodium hydrogensulfite; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; carbonylhydridetris(triphenylphosphine)rhodium(I) / water / 1 h / 70 °C / 6750.68 Torr / Inert atmosphere; Microwave irradiation
With
carbonylhydridetris(triphenylphosphine)rhodium(I); thionyl chloride; hydrogen; sodium hydrogensulfite; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene;
In
dichloromethane; water;
DOI:10.1002/cctc.202100181
- Guidance literature:
-
Multi-step reaction with 2 steps
1: triethylamine / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere
2: hydrogen; sodium hydrogensulfite; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; carbonylhydridetris(triphenylphosphine)rhodium(I) / water / 1 h / 70 °C / 6750.68 Torr / Inert atmosphere; Microwave irradiation
With
carbonylhydridetris(triphenylphosphine)rhodium(I); hydrogen; sodium hydrogensulfite; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene;
In
dichloromethane; water;
DOI:10.1002/cctc.202100181
