3,5-dimethyl-7H-furo[3,2-g]chromen-7-one

Base Information

• Chemical Name: 3,5-dimethyl-7H-furo[3,2-g]chromen-7-one
• CAS No.: 15183-96-7
• Molecular Formula: C₁₃H₁₀O₃
• Molecular Weight: 214.221
• Mol file: 15183-96-7.mol

Synonyms:5-Benzofuranacrylicacid, 6-hydroxy-b,3-dimethyl-,d-lactone (6CI,7CI);4,4'-Dimethylpsoralen; 4,6-Dimethylpsoralen; 4,6-Dimethylpsoralene

Chemical Property of 3,5-dimethyl-7H-furo[3,2-g]chromen-7-one

Chemical Property:

• Vapor Pressure: 4.11E-06mmHg at 25°C
• Boiling Point: 384.4°Cat760mmHg
• Flash Point: 186.3°C
• PSA: 43.35000
• Density: 1.273g/cm³
• LogP: 3.15600

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-dimethyl-7H-furo[3,2-g]chromen-7-one

There total 9 articles about 3,5-dimethyl-7H-furo[3,2-g]chromen-7-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

4-methyl-7-(2-oxopropoxy)-2H-1-benzopyran-2-one (68454-18-2) → 3,5-dimethyl-7H-furo[3,2-g]chromen-7-one (15183-96-7)

Guidance literature:

With sodium hydroxide; for 2h; Heating;

DOI:10.1016/j.ejmech.2005.07.014

Reference yield: 59.0%

3-methylbenzofuran-6-ol (3652-66-2) + ethyl acetoacetate (141-97-9) → 3,5-dimethyl-7H-furo[3,2-g]chromen-7-one (15183-96-7)

Guidance literature:

With aluminum oxide; zinc(II) chloride; for 0.0533333h; microwave irradiation;

DOI:10.1080/10426500307819

Reference yield:

7-hydroxy-4-methyl-chromen-2-one (90-33-5,79566-13-5) → 3,5-dimethyl-7H-furo[3,2-g]chromen-7-one (15183-96-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / K₂CO₃ / acetone / 72 h / Heating

2: 83 percent / aq. NaOH / 2 h / Heating

With sodium hydroxide; potassium carbonate; In acetone;

DOI:10.1016/j.ejmech.2005.07.014

upstream raw materials:

ethanol

4-methyl-7-(2-oxopropoxy)-2H-1-benzopyran-2-one

sodium ethanolate

(6-acetyl-4-methyl-2-oxo-2H-chromen-7-yloxy)-acetic acid