4-Amino-2-(benzyloxy)benzonitrile

Base Information

Chemical Name:4-Amino-2-(benzyloxy)benzonitrile
CAS No.:284044-40-2
Molecular Formula:C14H12N2O
Molecular Weight:224.262
Hs Code.:
DSSTox Substance ID:DTXSID001285322
Mol file:284044-40-2.mol

Synonyms:284044-40-2;Benzonitrile, 4-amino-2-(phenylmethoxy)-;4-amino-2-(benzyloxy)benzonitrile;4-amino-2-phenylmethoxybenzonitrile;SCHEMBL2700393;DTXSID001285322;MFCD13192719;4-Amino-2-(phenylmethoxy)benzonitrile;AKOS037644444;4-amino-2-(phenylmethoxy)-benzonitrile;Benzonitrile,4-amino-2-(phenylmethoxy)-;AS-53672;CS-0098252;P16859;A1-11956

Suppliers and Price of 4-Amino-2-(benzyloxy)benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-Amino-2-(benzyloxy)benzonitrile

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:224.094963011
Heavy Atom Count:17
Complexity:277

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=C(C=CC(=C2)N)C#N

Technology Process of 4-Amino-2-(benzyloxy)benzonitrile

There total 5 articles about 4-Amino-2-(benzyloxy)benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 380241-64-5
2-(benzyloxy)-4-nitrobenzonitrile

: 284044-40-2
4-amino-2-(benzyloxy)benzonitrile

Guidance literature:: With hydrogenchloride; tin(ll) chloride; In 1,4-dioxane;
DOI:10.1021/jm010244+

Reference yield:

: 39835-14-8
2-hydroxy-4-nitro-benzonitrile

: 100-39-0
benzyl bromide

: 284044-40-2
4-amino-2-(benzyloxy)benzonitrile

Guidance literature:: 2-hydroxy-4-nitro-benzonitrile; benzyl bromide; With potassium carbonate; In DMF (N,N-dimethyl-formamide); at 20 ℃;

With hydrogen; platinum on carbon; In ethyl acetate;

Reference yield:

: 39835-14-8
2-hydroxy-4-nitro-benzonitrile

: 284044-40-2
4-amino-2-(benzyloxy)benzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / K₂CO₃ / 2 h

2: 100 percent / SnCl₂*2H₂O; 6 N aq. HCl / dioxane

With hydrogenchloride; potassium carbonate; tin(ll) chloride; In 1,4-dioxane;
DOI:10.1021/jm010244+