Tert-butyl [(6-chloropyridin-3-yl)methyl]carbamate

Base Information

Chemical Name:Tert-butyl [(6-chloropyridin-3-yl)methyl]carbamate
CAS No.:285119-72-4
Molecular Formula:C11H15ClN2O2
Molecular Weight:242.705
Hs Code.:2933399090
DSSTox Substance ID:DTXSID80572891
Nikkaji Number:J1.319.217K
Wikidata:Q82461397
Mol file:285119-72-4.mol

Synonyms:285119-72-4;tert-butyl [(6-chloropyridin-3-yl)methyl]carbamate;tert-Butyl ((6-chloropyridin-3-yl)methyl)carbamate;tert-butyl N-[(6-chloropyridin-3-yl)methyl]carbamate;tert-Butyl (6-chloro-pyridin-3-ylmethyl)-carbamate;tert-butyl [(6-chloro-3-pyridinyl)methyl]carbamate;tert-Butyl((6-chloropyridin-3-yl)methyl)carbamate;Tert-butyl[(6-chloropyridin-3-yl)methyl]carbamate;Carbamic acid, N-[(6-chloro-3-pyridinyl)methyl]-, 1,1-dimethylethyl ester;SCHEMBL506742;DTXSID80572891;MGMROIDEKDNQND-UHFFFAOYSA-N;MFCD11974332;AKOS005173718;SB36378;AS-47098;CS-0154383;F12036;EN300-7184649;3-(tert-Butoxycarbonylamino-methyl)-6-chloropyridine;J-017109;5-(tert-butoxycarbonylamino-methyl)-2-chloro-pyridine

Suppliers and Price of Tert-butyl [(6-chloropyridin-3-yl)methyl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
tert-Butyl [(6-chloropyridin-3-yl)methyl]carbamate
500mg
$ 394.00

J&W Pharmlab
tert-Butyl(6-chloro-pyridin-3-ylmethyl)-carbamate 96%
5g
$ 2998.00

J&W Pharmlab
tert-Butyl(6-chloro-pyridin-3-ylmethyl)-carbamate 96%
1g
$ 798.00

Crysdot
tert-Butyl((6-chloropyridin-3-yl)methyl)carbamate 95+%
5g
$ 430.00

Chemenu
tert-Butyl[(6-chloropyridin-3-yl)methyl]carbamate 95%
5g
$ 406.00

ChemBridge Corporation
tert-butyl[(6-chloro-3-pyridinyl)methyl]carbamate 95%
5 g
$ 795.00

ChemBridge Corporation
tert-butyl[(6-chloro-3-pyridinyl)methyl]carbamate 95%
1 g
$ 235.00

Biosynth Carbosynth
tert-Butyl [(6-chloropyridin-3-yl)methyl]carbamate
100 mg
$ 150.00

Biosynth Carbosynth
tert-Butyl [(6-chloropyridin-3-yl)methyl]carbamate
50 mg
$ 95.00

Biosynth Carbosynth
tert-Butyl [(6-chloropyridin-3-yl)methyl]carbamate
25 mg
$ 60.00

Total 18 raw suppliers

Chemical Property of Tert-butyl [(6-chloropyridin-3-yl)methyl]carbamate

Chemical Property:

Melting Point:43-44 °C
Boiling Point:376.3±32.0 °C(Predicted)
PKA:11.33±0.46(Predicted)
PSA：51.22000
Density:1.179±0.06 g/cm3(Predicted)
LogP:3.15060
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:242.0822054
Heavy Atom Count:16
Complexity:241

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl [(6-chloropyridin-3-yl)methyl]carbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCC1=CN=C(C=C1)Cl

Technology Process of Tert-butyl [(6-chloropyridin-3-yl)methyl]carbamate

There total 3 articles about Tert-butyl [(6-chloropyridin-3-yl)methyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 97004-04-1
5-(aminomethyl)-2-chloropyridine

: 285119-72-4
(6-chloropyridin-3-ylmethyl)carbamic acid tert-butyl ester

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃;

Reference yield: 93.0%

: 33252-28-7
6-chloronicotinonitrile

: 24424-99-5
di-tert-butyl dicarbonate

: 285119-72-4
(6-chloropyridin-3-ylmethyl)carbamic acid tert-butyl ester

Guidance literature:: With sodium tetrahydroborate; nickel dichloride; In methanol; at 0 - 20 ℃; for 1h;
DOI:10.1016/S0040-4020(03)00858-5

Reference yield: 86.0%

: 69045-79-0
2-choro-5-iodopyridine

: 91837-43-3
1,3-dioxoisoindolin-2-yl (tert-butoxycarbonyl)glycinate

: 285119-72-4
(6-chloropyridin-3-ylmethyl)carbamic acid tert-butyl ester

Guidance literature:: With chloro-trimethyl-silane; (1,2-dimethoxyethane)dichloronickel(II); pyridine-2-carboxamidine hydrochloride; 1-Bromo-2-chloroethane; zinc; In tetrahydrofuran; N,N-dimethyl acetamide; at 30 ℃; Inert atmosphere; Flow reactor;
DOI:10.1002/chem.201905048