4H-1-Benzopyran-4-one, 3,5-bis(acetyloxy)-2-[4-(acetyloxy)phenyl]-6,7-dimethoxy-

Base Information

• Chemical Name: 4H-1-Benzopyran-4-one, 3,5-bis(acetyloxy)-2-[4-(acetyloxy)phenyl]-6,7-dimethoxy-
• CAS No.: 29536-43-4
• Molecular Formula: C₂₃H₂₀O₁₀
• Molecular Weight: 456.406
• Mol file: 29536-43-4.mol

Synonyms:

Chemical Property of 4H-1-Benzopyran-4-one, 3,5-bis(acetyloxy)-2-[4-(acetyloxy)phenyl]-6,7-dimethoxy-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4H-1-Benzopyran-4-one, 3,5-bis(acetyloxy)-2-[4-(acetyloxy)phenyl]-6,7-dimethoxy-

There total 8 articles about 4H-1-Benzopyran-4-one, 3,5-bis(acetyloxy)-2-[4-(acetyloxy)phenyl]-6,7-dimethoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-(benzyloxy)benzoic acid anhydride (1486-49-3) → 3,5-diacetoxy-2-(4-acetoxy-phenyl)-6,7-dimethoxy-chromen-4-one (29536-43-4)

Guidance literature:

Multi-step reaction with 7 steps

1: 1.) potassium benzoate, 2.) K₂CO₃ / 1.) 170/180 deg C, 8 h, 2.) acetone, reflux, 2.5-4 h

2: 88 percent / AlBr₃ / acetonitrile / 0.33 h / 0 - 5 °C

3: 82 percent / K₂CO₃ / acetone / Heating

4: 91 percent / AlBr₃ / acetonitrile / 1 h / Ambient temperature

5: 86 percent / K₂CO₃ / methanol / 2 h / Heating

6: 85 percent / H₂ / 10percent palladium on charcoal / ethyl acetate; methanol

7: pyridine / 24 h / Ambient temperature

With pyridine; aluminum tri-bromide; hydrogen; Potassium benzoate; potassium carbonate; palladium on activated charcoal; In methanol; ethyl acetate; acetone; acetonitrile;

Reference yield:

1-(3,6-dihydroxy-2,4-dimethoxy-phenyl)-2-methoxy-ethanone (14639-73-7) → 3,5-diacetoxy-2-(4-acetoxy-phenyl)-6,7-dimethoxy-chromen-4-one (29536-43-4)

Guidance literature:

Multi-step reaction with 7 steps

1: 1.) potassium benzoate, 2.) K₂CO₃ / 1.) 170/180 deg C, 8 h, 2.) acetone, reflux, 2.5-4 h

2: 88 percent / AlBr₃ / acetonitrile / 0.33 h / 0 - 5 °C

3: 82 percent / K₂CO₃ / acetone / Heating

4: 91 percent / AlBr₃ / acetonitrile / 1 h / Ambient temperature

5: 86 percent / K₂CO₃ / methanol / 2 h / Heating

6: 85 percent / H₂ / 10percent palladium on charcoal / ethyl acetate; methanol

7: pyridine / 24 h / Ambient temperature

With pyridine; aluminum tri-bromide; hydrogen; Potassium benzoate; potassium carbonate; palladium on activated charcoal; In methanol; ethyl acetate; acetone; acetonitrile;

Reference yield:

2-(4-benzyloxy-phenyl)-5-hydroxy-3,6,7-trimethoxy-chromen-4-one (14801-90-2) → 3,5-diacetoxy-2-(4-acetoxy-phenyl)-6,7-dimethoxy-chromen-4-one (29536-43-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 82 percent / K₂CO₃ / acetone / Heating

2: 91 percent / AlBr₃ / acetonitrile / 1 h / Ambient temperature

3: 86 percent / K₂CO₃ / methanol / 2 h / Heating

4: 85 percent / H₂ / 10percent palladium on charcoal / ethyl acetate; methanol

5: pyridine / 24 h / Ambient temperature

With pyridine; aluminum tri-bromide; hydrogen; potassium carbonate; palladium on activated charcoal; In methanol; ethyl acetate; acetone; acetonitrile;

upstream raw materials:

p-(benzyloxy)benzoic acid anhydride

1-(3,6-dihydroxy-2,4-dimethoxy-phenyl)-2-methoxy-ethanone

2-(4-benzyloxy-phenyl)-5-hydroxy-3,6,7-trimethoxy-chromen-4-one

2-(4-Benzyloxy-phenyl)-3,5-dihydroxy-6,7-dimethoxy-chromen-4-one