3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexan-1-one

Base Information

Chemical Name:3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexan-1-one
CAS No.:302577-72-6
Molecular Formula:C12H21BO3
Molecular Weight:224.10400
Hs Code.:2934999090
DSSTox Substance ID:DTXSID40465452
Nikkaji Number:J1.368.937G
Mol file:302577-72-6.mol

Synonyms:302577-72-6;3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexan-1-one;3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexanone;3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexan-1-one;Cyclohexanone, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-;DTXSID40465452;MFCD18447549;AKOS025146540;AS-55082;CS-0174268;EN300-370614;W13778;Z2049748083

Suppliers and Price of 3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexan-1-one
50mg
$ 45.00

Crysdot
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexanone 95+%
5g
$ 452.00

AK Scientific
3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexan-1-one
5g
$ 691.00

Total 7 raw suppliers

Chemical Property of 3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexan-1-one

Chemical Property:

PSA：35.53000
LogP:2.59190
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:224.1583747
Heavy Atom Count:16
Complexity:283

Purity/Quality:

98+% ^*data from raw suppliers

3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexan-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2CCCC(=O)C2

Technology Process of 3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexan-1-one

There total 9 articles about 3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 930-68-7
cyclohexenone

: 73183-34-3
bis(pinacol)diborane

: 302577-72-6
3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexan-1-one

Guidance literature:: cyclohexenone; bis(pinacol)diborane; With potassium carbonate; In methanol; toluene; at 60 ℃; for 2h; Inert atmosphere;

With water; ammonium chloride; In methanol; toluene; Inert atmosphere;
DOI:10.1021/jo100325e

Reference yield: 94.0%

: 930-68-7
cyclohexenone

: 73183-34-3
bis(pinacol)diborane

: 1201815-97-5,302577-72-6
(R)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexanone

Guidance literature:: With [CN₂(C₆H₄-2-iPr₃C₆H₂)(C₆H₃-2-Me-6-iPr)C₂H₂Ph₂]BF₄; 1,8-diazabicyclo[5.4.0]undec-7-ene; MeOH; In tetrahydrofuran; (N2), 22°C, 14 h;
DOI:10.1021/ja302929d

Reference yield: 90.0%

: 930-68-7
cyclohexenone

: 73183-34-3
bis(pinacol)diborane

: 1201815-98-6,302577-72-6
(S)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexanone

Guidance literature:: With methanol; C₄₁H₃₇FeP₂; copper(l) chloride; sodium t-butanolate; In tetrahydrofuran; at 20 ℃; for 24h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1039/b914207j