1,1'-(Benzylimino)bisethanone

Base Information

• Chemical Name: 1,1'-(Benzylimino)bisethanone
• CAS No.: 3027-02-9
• Molecular Formula: C11H13NO2
• Molecular Weight: 191.23
• Hs Code.: 2925190090
• Mol file: 3027-02-9.mol

Synonyms:Diacetyl-benzylamin;diacetylbenzylamine;N-benzyl-diacetamide;N,N-Diacetylbenzylamin;N-Benzyl-diacetamid;N-Benzyl-diacetyl-amin;

Chemical Property of 1,1'-(Benzylimino)bisethanone

Chemical Property:

• PSA: 37.38000
• LogP: 1.58160
• Storage Temp.: Refrigerator
• Solubility.: Chloroform, Methanol

Purity/Quality:

99% ^*data from raw suppliers

N-Benzyldiacetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-Benzyldiacetamide is an intermediate in the synthesis of labelled N-Nitrosodiethylamine (N525465), a widely occurring nitrosamine that is one of the most important environmental carcinogens primarily inducing tumors of liver.

Technology Process of 1,1'-(Benzylimino)bisethanone

There total 20 articles about 1,1'-(Benzylimino)bisethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

N-benzylthioacetamide (14309-88-7) + acetic acid (64-19-7,77671-22-8) → N-acetyl-N-benzylacetamide (3027-02-9)

Guidance literature:

With silver carbonate; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1039/c4cc07601j

Reference yield: 86.0%

benzonitrile (100-47-0) + acetyl chloride (75-36-5) → N-acetyl-N-benzylacetamide (3027-02-9)

Guidance literature:

benzonitrile; With cobalt pivalate; 1,1,3,3-Tetramethyldisiloxane; tert-butylisonitrile; at 80 ℃; for 24h;

acetyl chloride; In dichloromethane; at 50 ℃; for 24h;

DOI:10.1021/acs.orglett.8b03736

Reference yield: 75.0%

acetyl chloride (75-36-5) + benzylamine (100-46-9) → N-acetyl-N-benzylacetamide (3027-02-9)

Guidance literature:

With pyridine; for 2h; Heating;

DOI:10.1002/kin.550260909

upstream raw materials:

tris-benzylamino-propyl-silane

acetic anhydride

trimethylsilyl acetate

N-(phenylmethyl)acetamide

Downstream raw materials:

bis(4-hydroxy-1-naphtyl)phenylmethane