Benzene, (1,1-dichloro-2,2,2-trifluoroethyl)-

Base Information

• Chemical Name: Benzene, (1,1-dichloro-2,2,2-trifluoroethyl)-
• CAS No.: 309-10-4
• Molecular Formula: C8H5Cl2F3
• Molecular Weight: 229.029
• Mol file: 309-10-4.mol

Synonyms:

Chemical Property of Benzene, (1,1-dichloro-2,2,2-trifluoroethyl)-

Chemical Property:

Purity/Quality:

98.5% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzene, (1,1-dichloro-2,2,2-trifluoroethyl)-

There total 4 articles about Benzene, (1,1-dichloro-2,2,2-trifluoroethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2,2-Trifluoroacetophenone (434-45-7) → 1,1,1-trifluoro-2,2-dichloro-2-phenylethane (309-10-4)

Guidance literature:

With phosphorus pentachloride; at 175 ℃;

DOI:10.1021/ja01178a052 DOI:10.1021/ja01243a024

Reference yield:

2,2,2-Trifluoroacetophenone (434-45-7) + phosphorus pentachloride (10026-13-8,874483-75-7) → 1,1,1-trifluoro-2,2-dichloro-2-phenylethane (309-10-4)

Guidance literature:

at 175 ℃;

DOI:10.1021/ja01178a052 DOI:10.1021/ja01243a024

Reference yield:

(2,2,2-trifluoroethyl)benzene (21249-93-4) → 1-chloro-2,2,2-trifluoroethylbenzene (384-65-6) + 1,1,1-trifluoro-2,2-dichloro-2-phenylethane (309-10-4)

Guidance literature:

With sulfuryl dichloride; 2,2'-azobis(isobutyronitrile); In benzene; at 40 ℃; Product distribution; Mechanism; Irradiation; relative rate const. to toluene, m-FC₆H₄CH₂Cl and XC₆H₅CH₂CF₃ (X= p-Cl, m-Cl m-CF₃);isotopic effect; correlation between log k and Brown's const.; the method of competing reaction;;

upstream raw materials:

2,2,2-Trifluoroacetophenone

(2,2,2-trifluoroethyl)benzene

1,1,1-trifluoro-2-phenylethane-2,2-d₂

phosphorus pentachloride

Downstream raw materials:

α-chloro-β,β-difluorostyrene

2',2'-difluorostyrene

1-chloro-3-(1,1-dichloro-2,2,2-trifluoro-ethyl)-benzene

(1-chloro-1,2,2,2-tetrafluoro-ethyl)-benzene

Refernces

• 1、 Simons,Ramler. "-". . p. 389,390. Retrieved 1943.