3alpha,17-Dihydroxy-5alpha-pregnan-20-one

Base Information

Chemical Name:3alpha,17-Dihydroxy-5alpha-pregnan-20-one
CAS No.:6890-65-9
Molecular Formula:C21H34 O3
Molecular Weight:334.499
Hs Code.:
European Community (EC) Number:229-994-6
DSSTox Substance ID:DTXSID701290974
Nikkaji Number:J265.944A
Wikidata:Q100716337
Mol file:6890-65-9.mol

Synonyms:5 beta-pregnane-3 alpha,17 alpha-diol-11,20-dione;5alpha-pregnane-3alpha,17alpha-diol-20-one;pregnane-3,17-diol-11,20-dione;pregnane-3,17-diol-11,20-dione, (3alpha,5alpha)-isomer;pregnane-3,17-diol-11,20-dione, (3alpha,5beta)-isomer;pregnane-3,17-diol-11,20-dione, (3beta,5alpha)-isomer

Suppliers and Price of 3alpha,17-Dihydroxy-5alpha-pregnan-20-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
5α-Pregnane-3α,17α-diol-20-one
1 mg
$ 190.00

Total 7 raw suppliers

Chemical Property of 3alpha,17-Dihydroxy-5alpha-pregnan-20-one

Chemical Property:

Boiling Point:465.4oC at 760 mmHg
Flash Point:249.4oC
PSA：57.53000
Density:1.123g/cm3
LogP:3.71010
XLogP3:3.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:334.25079494
Heavy Atom Count:24
Complexity:545

Purity/Quality:

99% ^*data from raw suppliers

5α-Pregnane-3α,17α-diol-20-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1(CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C)O
Isomeric SMILES:CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@H](C4)O)C)C)O
Uses (3α,5α)-3,17-Dihydroxypregnan-20-one has been studied has a metabolite of research interest in the study of human male testes diseases or aberration pertaining androgen-mediated events in male puberty; such as biosynthesis of testosterone, adrenocortical carcinoma, castration-resistant prostate cancer and urine steroid hormone profiling.

Technology Process of 3alpha,17-Dihydroxy-5alpha-pregnan-20-one

There total 13 articles about 3alpha,17-Dihydroxy-5alpha-pregnan-20-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 57-83-0
Progesterone

: 566-65-4
dihydroprogesterone

: 846-46-8
androstanedione

: 516-55-2
isopregnanolone

: 570-54-7
3β,17α-dihydroxy-5α-pregnan-20-one

: 516-54-1
tetrahydroprogesterone

: 6890-65-9
3α,17α-dihydroxy-5α-pregnan-20-one

Guidance literature:: With total testicular homogenate of adult Sprague-Dawley rats treated with 6, des-Gly-NH2¹⁰>LHRH ethylamide; Product distribution; metabolism, <3H>labelled, further: equine antibovine LH serum (JOAN-5-31-67);
DOI:10.1016/0039-128X(84)90054-0