1,3-Dihydro-1,3-dimethyl-2,1,3-benzothiadiazole 2,2-dioxide

Base Information

• Chemical Name: 1,3-Dihydro-1,3-dimethyl-2,1,3-benzothiadiazole 2,2-dioxide
• CAS No.: 31378-12-8
• Molecular Formula: C8H10N2O2S
• Molecular Weight: 198.24200
• Mol file: 31378-12-8.mol

Synonyms:1,3-Dimethyl-1,3-dihydro-benzo[1,2,5]thiadiazole 2,2-dioxide;1,3-Dimethyl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide;1,3-Dimethyl-1H,2H-2,1,3-benzothiadiazolin-2,2-dioxid;

Chemical Property of 1,3-Dihydro-1,3-dimethyl-2,1,3-benzothiadiazole 2,2-dioxide

Chemical Property:

• PSA: 49.00000
• LogP: 2.02820

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-Dihydro-1,3-dimethyl-2,1,3-benzothiadiazole 2,2-dioxide

There total 3 articles about 1,3-Dihydro-1,3-dimethyl-2,1,3-benzothiadiazole 2,2-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl iodide (74-88-4) → 1,3-dimethyl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide (31378-12-8)

Guidance literature:

1,3-dihydrobenzo[c][1,2,5]thiadiazole 2,2-dioxide; With sodium hydride; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 1h;

methyl iodide; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 18h;

Reference yield:

1,3-dihydrobenzo[c][1,2,5]thiadiazole 2,2-dioxide (1615-06-1) + methyl iodide (74-88-4) → 1,3-dimethyl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide (31378-12-8)

Guidance literature:

1,3-dihydrobenzo[c][1,2,5]thiadiazole 2,2-dioxide; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.5h; Inert atmosphere;

methyl iodide; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 1h; Inert atmosphere;

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + 1,3-dihydrobenzo[c][1,2,5]thiadiazole 2,2-dioxide (1615-06-1) → 1,3-dimethyl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide (31378-12-8)

Guidance literature:

In diethyl ether;

DOI:10.1039/j39710000993

upstream raw materials:

diazomethane

1,3-dihydrobenzo[c][1,2,5]thiadiazole 2,2-dioxide

methyl iodide