1-(Chloromethyl)-2,5-dimethoxy-4-methylbenzene

Base Information

Chemical Name:1-(Chloromethyl)-2,5-dimethoxy-4-methylbenzene
CAS No.:32378-21-5
Molecular Formula:C10H13ClO2
Molecular Weight:200.665
Hs Code.:
DSSTox Substance ID:DTXSID40491014
Wikidata:Q82335153
Mol file:32378-21-5.mol

Synonyms:32378-21-5;1-(Chloromethyl)-2,5-dimethoxy-4-methylbenzene;SCHEMBL10730344;DTXSID40491014

Suppliers and Price of 1-(Chloromethyl)-2,5-dimethoxy-4-methylbenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-(Chloromethyl)-2,5-dimethoxy-4-methylbenzene

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:200.0604073
Heavy Atom Count:13
Complexity:152

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1OC)CCl)OC

Technology Process of 1-(Chloromethyl)-2,5-dimethoxy-4-methylbenzene

There total 11 articles about 1-(Chloromethyl)-2,5-dimethoxy-4-methylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 32176-96-8
2,5-dimethoxy-4-methylphenylmethanol

: 32378-21-5
2-(Chloromethyl)-5-methyl-1,4-dimethoxybenzene

Guidance literature:: With pyridine; thionyl chloride; In benzene; Heating;

Reference yield:

: 65109-51-5
2-(Bromomethyl)-5-methyl-1,4-dimethoxybenzene

: 32378-21-5
2-(Chloromethyl)-5-methyl-1,4-dimethoxybenzene

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / methanol / 2 h / Ambient temperature

2: 1.) Orange CRET^.+, 2.) Zn / 1.) CH₂Cl₂, 0 deg C, 0.5 h, 2.) r.t., 5 min

3: ICl / CH₂Cl₂

With Orange CRET^.+; Iodine monochloride; zinc; In methanol; dichloromethane;
DOI:10.1021/jo00128a020

Reference yield:

: 32176-89-9
1,4-Dimethoxy-2-methoxymethyl-5-methyl-benzene

: 32378-21-5
2-(Chloromethyl)-5-methyl-1,4-dimethoxybenzene

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Orange CRET^.+, 2.) Zn / 1.) CH₂Cl₂, 0 deg C, 0.5 h, 2.) r.t., 5 min

2: ICl / CH₂Cl₂

With Orange CRET^.+; Iodine monochloride; zinc; In dichloromethane;
DOI:10.1021/jo00128a020