3,5-ditert-butyl-1-[(3,5-ditert-butyl-1H-pyrazol-1-yl)methyl]-1H-pyrazole

Base Information

• Chemical Name: 3,5-ditert-butyl-1-[(3,5-ditert-butyl-1H-pyrazol-1-yl)methyl]-1H-pyrazole
• CAS No.: 331943-39-6
• Molecular Formula: C23H40N4
• Molecular Weight: 372.597
• Mol file: 331943-39-6.mol

Synonyms:bis-(3,5-di-tert-butyl-1H-pyrazol-1-yl)methane;bis(3,5-di-tertbutylpyrazol-1-yl)methane;bis(3,5-di-tert-butylpyrazol-1-yl)methane;bis(3,5-di-t-butylpyrazol-1-yl)methane;bis(3,5-di-tert-butyl-1-pyrazolyl)methane;methylenebis(3,5-di(t-butyl)pyrazole);

Chemical Property of 3,5-ditert-butyl-1-[(3,5-ditert-butyl-1H-pyrazol-1-yl)methyl]-1H-pyrazole

Chemical Property:

• PSA: 35.64000
• LogP: 5.77540

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5-ditert-butyl-1-[(3,5-ditert-butyl-1H-pyrazol-1-yl)methyl]-1H-pyrazole

There total 3 articles about 3,5-ditert-butyl-1-[(3,5-ditert-butyl-1H-pyrazol-1-yl)methyl]-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

dichloromethane (75-09-2) + 3,5-di-tert-butylpyrazole (1132-14-5) → bis-(3,5-di-tert-butyl-1H-pyrazol-1-yl)methane (331943-39-6)

Guidance literature:

With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate; for 5h; Heating;

Reference yield: 63.0%

3,5-dimethyl-1H-pyrazole (67-51-6) + dichloromethane (75-09-2) + 3,5-di-tert-butylpyrazole (1132-14-5) → 1,1'-methylenebis(3,5-dimethyl-1H-pyrazole) (28791-82-4) + bis-(3,5-di-tert-butyl-1H-pyrazol-1-yl)methane (331943-39-6) + 3,5-di-tert-butyl-1-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-1H-pyrazole (536753-70-5)

Guidance literature:

With potassium hydroxide; potassium carbonate; N-benzyl-N,N,N-triethylammonium chloride; for 12h; Heating;

DOI:10.1002/ejic.200390046

Reference yield:

potassium carbonate (584-08-7) + 3,5-di-tert-butylpyrazole (1132-14-5) → bis-(3,5-di-tert-butyl-1H-pyrazol-1-yl)methane (331943-39-6)

Guidance literature:

With N-benzyl-N,N,N-triethylammonium chloride; potassium hydroxide; In dichloromethane;

DOI:10.1007/s10562-018-2477-2

upstream raw materials:

dichloromethane

3,5-di-tert-butylpyrazole

3,5-dimethyl-1H-pyrazole

potassium carbonate

Downstream raw materials:

lithium N-phenyl-2,2-bis(3,5-di-tert-butylpyrazol-1-yl)ethanimidothioate