3,4-DIHYDRO-1-NAPHTHOICACID

Base Information

• Chemical Name: 3,4-DIHYDRO-1-NAPHTHOICACID
• CAS No.: 3333-23-1
• Molecular Formula: C11H10O2
• Molecular Weight: 174.199
• Hs Code.: 2916399090
• Mol file: 3333-23-1.mol

Synonyms:1-Naphthalenecarboxylic acid,3,4-dihydro;1-Naphthalenecarboxylic acid, 3,4-dihydro-;3,4 Dihydro-napthalene-1-carboxylic acid;3,4-dihydro-1-naphthalenecarboxylic acid;

Chemical Property of 3,4-DIHYDRO-1-NAPHTHOICACID

Chemical Property:

• Melting Point: 125°C
• Refractive Index: 1.5520 (estimate)
• Boiling Point: 306°C (estimate)
• PKA: 4.21±0.20(Predicted)
• PSA: 37.30000
• Density: 1.0844 (rough estimate)
• LogP: 2.10080

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,4-DIHYDRO-1-NAPHTHOICACID

There total 2 articles about 3,4-DIHYDRO-1-NAPHTHOICACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

1-naphthalenecarboxylic acid (86-55-5) → tetralin-1-carboxylic acid (1914-65-4) + 1,4-dihydro-1-naphthalenecarboxylic acid (5111-73-9) + 3,4-dihydronaphthalene-1-carboxylic acid (3333-23-1)

Guidance literature:

With sodium hydroxide; In isopropyl alcohol; at 20 ℃; for 6h; UV-irradiation;

DOI:10.1016/j.tetlet.2008.03.123

Reference yield:

1-naphthalenecarboxylic acid (86-55-5) → tetralin-1-carboxylic acid (1914-65-4) + 3,4-dihydronaphthalene-1-carboxylic acid (3333-23-1)

Guidance literature:

Reference yield: 93.0%

3-Phenylpropenol (104-54-1) + 3,4-dihydronaphthalene-1-carboxylic acid (3333-23-1) → cinnamyl 3,4-dihydronaphthalene-1-carboxylate

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1002/anie.201904411

upstream raw materials:

1-naphthalenecarboxylic acid

Downstream raw materials:

tetralin-1-carboxylic acid

1-naphthalenecarboxylic acid

3,4-dihydro-[1]naphthoyl chloride

2-(2-carboxyethyl)benzoic acid

Refernces