Furan, 2-(4-bromophenyl)-5-methyl-

Base Information

• Chemical Name: Furan, 2-(4-bromophenyl)-5-methyl-
• CAS No.: 33342-24-4
• Molecular Formula: C11H9BrO
• Molecular Weight: 237.096
• Mol file: 33342-24-4.mol

Synonyms:

Chemical Property of Furan, 2-(4-bromophenyl)-5-methyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Furan, 2-(4-bromophenyl)-5-methyl-

There total 4 articles about Furan, 2-(4-bromophenyl)-5-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

2-methylfuran (534-22-5) + 1.4-dibromobenzene (106-37-6) → 2-(4-bromophenyl)-5-methylfuran (33342-24-4)

Guidance literature:

With [Pd(IPr*IMe)^An(3-Cl-pyridinyl)Cl₂]; potassium carbonate; acetic acid; In N,N-dimethyl acetamide; at 130 ℃; for 12h; regioselective reaction;

DOI:10.1021/acs.organomet.0c00494

Reference yield: 53.0%

1-(p-bromophenyl)prop-2-en-1-ol (58824-56-9) + methyl vinyl ketone (78-94-4,25038-87-3) → 2-(4-bromophenyl)-5-methylfuran (33342-24-4)

Guidance literature:

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; pyridinium p-toluenesulfonate; In dichloromethane; at -78 - 40 ℃; Inert atmosphere;

DOI:10.1073/pnas.0913466107

Reference yield: 16.0%

2-methylfuran (534-22-5) + 4-bromobenzenediazonium tetrafluoroborate (673-40-5) → 2-(4-bromophenyl)-5-methylfuran (33342-24-4)

Guidance literature:

With reduced base-treated graphene oxide; In dimethyl sulfoxide; at 40 ℃; for 6h; Inert atmosphere;

DOI:10.1039/c7cc02337e

upstream raw materials:

1-(p-bromophenyl)prop-2-en-1-ol

methyl vinyl ketone

2-methylfuran

4-bromobenzenediazonium tetrafluoroborate

Downstream raw materials:

2-(4-Bromo-phenyl)-5-methyl-selenophene

2-(p-bromophenyl)-5-methylthiophene

2-(p-Bromophenyl)-3-bromo-5-methylfuran

2-(p-Cyanophenyl)-3-cyano-5-methylfuran