Cyclopropanecarboxylic acid, 2-methyl-2-phenyl-, ethyl ester, (1R,2S)-

Base Information

Chemical Name:Cyclopropanecarboxylic acid, 2-methyl-2-phenyl-, ethyl ester, (1R,2S)-
CAS No.:335593-36-7
Molecular Formula:C13H16O2
Molecular Weight:204.269
Hs Code.:
DSSTox Substance ID:DTXSID30459421
Nikkaji Number:J850.672H
Wikidata:Q82283185

Synonyms:335593-36-7;Cyclopropanecarboxylic acid, 2-methyl-2-phenyl-, ethyl ester, (1R,2S)-;SCHEMBL15977390;DTXSID30459421;2alpha-Methyl-2-phenylcyclopropane-1beta-carboxylic acid ethyl ester

Suppliers and Price of Cyclopropanecarboxylic acid, 2-methyl-2-phenyl-, ethyl ester, (1R,2S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Cyclopropanecarboxylic acid, 2-methyl-2-phenyl-, ethyl ester, (1R,2S)-

Chemical Property:

Boiling Point:271.6±19.0 °C(Predicted)
PSA：26.30000
Density:1.075±0.06 g/cm3(Predicted)
LogP:2.52730
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:204.115029749
Heavy Atom Count:15
Complexity:243

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1CC1(C)C2=CC=CC=C2
Isomeric SMILES:CCOC(=O)[C@@H]1C[C@]1(C)C2=CC=CC=C2

Technology Process of Cyclopropanecarboxylic acid, 2-methyl-2-phenyl-, ethyl ester, (1R,2S)-

There total 9 articles about Cyclopropanecarboxylic acid, 2-methyl-2-phenyl-, ethyl ester, (1R,2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 623-73-4
diazoacetic acid ethyl ester

: 98-83-9,6144-04-3,25014-31-7,42612-14-6
isopropenylbenzene

: 160497-39-2
ethyl (1S,2R)-2-methyl-2-phenylcyclopropane-1-carboxylate

: ethyl trans-2-methyl-2-phenyl-cyclopropane-1-carboxylate

: 335593-36-7
ethyl (1R,2S)-2-methyl-2-phenylcyclopropane-1-carboxylate

Guidance literature:: With C₃₇H₄₀CuN₄O₄S₂⁽¹⁺⁾*CF₃O₃S^(1-); In hexane; at 0 ℃; Reagent/catalyst; Overall yield = 81 %Chromat.; stereoselective reaction; Inert atmosphere; Green chemistry;
DOI:10.1039/c3ra44806a

Reference yield:

: 623-73-4
diazoacetic acid ethyl ester

: 98-83-9,6144-04-3,25014-31-7,42612-14-6
isopropenylbenzene

: 160497-38-1
ethyl (1S,2S)-2-methyl-2-phenylcyclopropanecarboxylate

: 160497-39-2
ethyl (1S,2R)-2-methyl-2-phenylcyclopropane-1-carboxylate

: 335593-39-0
ethyl (1R,2R)-2-methyl-2-phenylcyclopropane-1-carboxylate

: 335593-36-7
ethyl (1R,2S)-2-methyl-2-phenylcyclopropane-1-carboxylate

Guidance literature:: chiral ruthenium complex; In dichloromethane; at 20 - 25 ℃; Title compound not separated from byproducts;
DOI:10.1016/S0040-4039(02)00317-9

Reference yield:

: 623-73-4
diazoacetic acid ethyl ester

: 98-83-9,6144-04-3,25014-31-7,42612-14-6
isopropenylbenzene

: 160497-39-2
ethyl (1S,2R)-2-methyl-2-phenylcyclopropane-1-carboxylate

: 36122-28-8
ethyl 2-methyl-2-phenylcyclopropane-1-carboxylate

: 335593-36-7
ethyl (1R,2S)-2-methyl-2-phenylcyclopropane-1-carboxylate

Guidance literature:: With 1-methyl-1H-imidazole; salcomine; In tetrahydrofuran; at 20 ℃; for 24h; Title compound not separated from byproducts;
DOI:10.1055/s-2006-926448