Ethyl 2-hydroxypropyl ketone

Base Information

• Chemical Name: Ethyl 2-hydroxypropyl ketone
• CAS No.: 33683-44-2
• Molecular Formula: C6H12O2
• Molecular Weight: 116.16
• Hs Code.: 2914400090
• Mol file: 33683-44-2.mol

Synonyms:Hexanol-(5)-on-(3);5-hydroxy-hexan-3-one;5-Hydroxy-hexan-3-on;3-Hexanone, 5-hydroxy-;

Chemical Property of Ethyl 2-hydroxypropyl ketone

Chemical Property:

• Melting Point: -3.75°C (estimate)
• Refractive Index: 1.4280
• Boiling Point: 212.22°C (estimate)
• PSA: 37.30000
• Density: 0.9500
• LogP: 0.73640

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethyl 2-hydroxypropyl ketone

There total 7 articles about Ethyl 2-hydroxypropyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

E-4-hexen-3-one (50396-96-8,130981-55-4,2497-21-4,50396-87-7) → 5-hydroxyhexan-3-one (33683-44-2)

Guidance literature:

With water; trimethylphosphane; at 20 ℃; for 20h;

DOI:10.1021/ja035232n

Reference yield:

C10H20O4 → 5-hydroxyhexan-3-one (33683-44-2)

Guidance literature:

With 10% Pd/C; hydrogen; In methanol; at 23 ℃; for 4h; under 760.051 Torr;

DOI:10.1021/ja802982h

Reference yield:

C10H20O3 (1037806-66-8) → 5-hydroxyhexan-3-one (33683-44-2)

Guidance literature:

With 10% Pd/C; hydrogen; In methanol; at 23 ℃; for 4h; under 760.051 Torr;

DOI:10.1021/ja802982h

upstream raw materials:

acetaldehyde

butanone

4-hydroxy-hex-3-en-2-one

methanol

Downstream raw materials:

4-hexen-3-one

hexan-3-one-(2,4-dinitro-phenylhydrazone)

n-hexan-3-one

Refernces

• 1、 Stewart, Ian C.,Bergman, Robert G.,Toste, F. Dean. "Phosphine-catalyzed hydration and hydroalkoxylation of activated olefins: Use of a strong nucleophile to generate a strong base". . p. 8696 - 8697. Retrieved 2007/10/03.