ARISTOLOCHIC ACID D(RG)(PLEASE CALL)

Base Information

• Chemical Name: ARISTOLOCHIC ACID D(RG)(PLEASE CALL)
• CAS No.: 17413-38-6
• Molecular Formula: C17H11NO8
• Molecular Weight: 357.276
• Mol file: 17413-38-6.mol

Synonyms:Aristolochicacid IVa (7CI);

Chemical Property of ARISTOLOCHIC ACID D(RG)(PLEASE CALL)

Chemical Property:

• Vapor Pressure: 5.83E-20mmHg at 25°C
• Melting Point: 262-263 °C(lit.)
• Refractive Index: 1.776
• Boiling Point: 689.5 °C at 760 mmHg
• Flash Point: 370.8 °C
• PSA: 131.04000
• Density: 1.656 g/cm³
• LogP: 3.56550

Purity/Quality:

98%Min ^*data from raw suppliers

AristolochicAcidD ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A derivative of carcinogenic Aristolochic acids (AAs).

Technology Process of ARISTOLOCHIC ACID D(RG)(PLEASE CALL)

There total 1 articles about ARISTOLOCHIC ACID D(RG)(PLEASE CALL) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

10-(β-D-glucosyloxy)-8-methoxy-6-nitrophenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid (84014-70-0) → 10-hydroxy-8-methoxy-6-nitrophenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid (17413-38-6) + D-glucose (50-99-7)

Guidance literature:

With hydrogenchloride; water; In methanol; at 20 ℃; for 5h;

DOI:10.4067/S0717-97072013000400041

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + 10-hydroxy-8-methoxy-6-nitrophenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid (17413-38-6) → aristolochic acid IV methyl ester (17448-02-1)

Guidance literature:

Yield given;

DOI:10.1016/S0031-9422(82)85055-3

upstream raw materials:

10-(β-D-glucosyloxy)-8-methoxy-6-nitrophenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid

Downstream raw materials:

aristolochic acid IV methyl ester

Refernces