N-(2,4,6-Tribromophenyl)formamide

Base Information

• Chemical Name: N-(2,4,6-Tribromophenyl)formamide
• CAS No.: 72002-23-4
• Molecular Formula: C7H4 Br3 N O
• Molecular Weight: 357.827
• European Community (EC) Number: 276-278-4
• DSSTox Substance ID: DTXSID801299543
• Nikkaji Number: J295.120G
• Mol file: 72002-23-4.mol

Synonyms:N-(2,4,6-Tribromophenyl)formamide;72002-23-4;EINECS 276-278-4;C7H4Br3NO;2,4,6-tribromophenylformamide;C7-H4-Br3-N-O;DTXSID801299543;AKOS014321917;AE-473/31468008

Chemical Property of N-(2,4,6-Tribromophenyl)formamide

Chemical Property:

• Vapor Pressure: 8.68E-08mmHg at 25°C
• Boiling Point: 435.5°C at 760 mmHg
• Flash Point: 217.2°C
• PSA: 32.59000
• Density: 2.312g/cm³
• LogP: 4.19190
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 356.78225
• Heavy Atom Count: 12
• Complexity: 155

Purity/Quality:

99% ^*data from raw suppliers

N-(2,4,6-TRIBROMOPHENYL)FORMAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1Br)NC=O)Br)Br

Technology Process of N-(2,4,6-Tribromophenyl)formamide

There total 7 articles about N-(2,4,6-Tribromophenyl)formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

chloroform (67-66-3,8013-54-5) + 2,4,6-tribromoaniline (147-82-0) → formic acid-(2,4,6-tribromo-anilide) (72002-23-4) + 2,4,6-Tribromophenyl isocyanide (2920-09-4)

Guidance literature:

With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; water; In dichloromethane; at 20 ℃;

Reference yield:

2,4,6-Tribromophenyl isocyanide (2920-09-4) → formic acid-(2,4,6-tribromo-anilide) (72002-23-4)

Guidance literature:

With water; trifluoroacetic acid; In chloroform;

Reference yield:

2,4,6-tribromoaniline (147-82-0) → formic acid-(2,4,6-tribromo-anilide) (72002-23-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 35 percent / KOH; H₂O; benzyltriethylammonium chloride / CH₂Cl₂ / 20 °C

2: H₂O; trifluoroacetic acid / CHCl₃

With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; water; trifluoroacetic acid; In dichloromethane; chloroform; 1: Addition / 2: Hydrolysis;

upstream raw materials:

formic acid

2,4,6-tribromoaniline

chloroform

2,4,6-Tribromophenyl isocyanide

Downstream raw materials:

2,4,6-Tribromophenyl isocyanide