2-[(3-Methoxyphenyl)methylamino]ethanol

Base Information

Chemical Name:2-[(3-Methoxyphenyl)methylamino]ethanol
CAS No.:33905-43-0
Molecular Formula:C10H15NO2
Molecular Weight:181.235
Hs Code.:
DSSTox Substance ID:DTXSID10405901
Wikidata:Q82210647

Synonyms:2-(3-Methoxy-benzylamino)-ethanol;2-[(3-methoxyphenyl)methylamino]ethanol;64834-62-4;33905-43-0;2-((3-Methoxybenzyl)amino)ethanol;SCHEMBL9416030;2-(3-Methoxybenzylamino)ethanol;DTXSID10405901;BQOZTZUPCCMROE-UHFFFAOYSA-N;AKOS002613960;SB85031;2-((3-Methoxybenzyl)amino)ethan-1-ol;AM101083;CS-0303097;2-{[(3-methoxyphenyl)methyl]amino}ethan-1-ol;EN300-168987

Suppliers and Price of 2-[(3-Methoxyphenyl)methylamino]ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[(3-Methoxyphenyl)methylamino]ethanol

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:181.110278721
Heavy Atom Count:13
Complexity:130

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1)CNCCO

Technology Process of 2-[(3-Methoxyphenyl)methylamino]ethanol

There total 8 articles about 2-[(3-Methoxyphenyl)methylamino]ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 109-83-1
(2-hydroxyethyl)(methyl)amine

: 766-85-8
3-methoxy-1-iodobenzene

: 33905-43-0
2-[(3-methoxyphenyl)-N-methylamino]ethanol

Guidance literature:: With copper(l) iodide; sodium hydroxide; In water; dimethyl sulfoxide; at 90 ℃; for 16h; Sealed tube; Inert atmosphere;
DOI:10.1002/chem.201403917

Reference yield: 72.4%

: 203580-74-9
ethyl 2-[(3-methoxyphenyl)-N-methylamino]acetate

: 33905-43-0
2-[(3-methoxyphenyl)-N-methylamino]ethanol

Guidance literature:: With sodium tetrahydroborate; lithium bromide; In tetrahydrofuran; for 5h; Reflux; Inert atmosphere;
DOI:10.1002/pola.24410

Reference yield:

: 536-90-3,918666-97-4
m-Anisidine

: 33905-43-0
2-[(3-methoxyphenyl)-N-methylamino]ethanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium methylate / methanol / 12 h / 20 °C

1.2: 2 h / 80 °C

2.1: sodium hydrogencarbonate / acetonitrile / 2 h / 90 °C

2.2: 16 h / 20 °C

3.1: sodium tetrahydroborate; lithium bromide / tetrahydrofuran / 21 h / 20 - 80 °C

With sodium tetrahydroborate; sodium methylate; sodium hydrogencarbonate; lithium bromide; In tetrahydrofuran; methanol; acetonitrile;