4-CHLORO-2,3-DIMETHYLPHENOL

Base Information

• Chemical Name: 4-CHLORO-2,3-DIMETHYLPHENOL
• CAS No.: 1570-76-9
• Molecular Formula: C8H9 Cl O
• Molecular Weight: 156.612
• Hs Code.: 2908199090
• Mol file: 1570-76-9.mol

Synonyms:2,3-Xylenol,4-chloro- (7CI,8CI); 4-Chloro-2,3-dimethylphenol; NSC 60150

Chemical Property of 4-CHLORO-2,3-DIMETHYLPHENOL

Chemical Property:

• PSA: 20.23000
• LogP: 2.66240

Purity/Quality:

99% ^*data from raw suppliers

4-Chloro-2,3-dimethylphenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-CHLORO-2,3-DIMETHYLPHENOL

There total 6 articles about 4-CHLORO-2,3-DIMETHYLPHENOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2,3-Dimethylphenol (526-75-0) → 2,3-dimethyl-4-chlorophenol (1570-76-9)

Guidance literature:

With N-chloro-succinimide; toluene-4-sulfonic acid; In acetonitrile; at 20 ℃; for 3h;

Reference yield:

2,3-Dimethylphenol (526-75-0) → 2,3-dimethyl-4-chlorophenol (1570-76-9) + 6-chloro-2,3-dimethylphenol (56961-15-0)

Guidance literature:

With sulfuryl dichloride; In tetrachloromethane; Yield given. Yields of byproduct given; Heating;

DOI:10.1271/bbb1961.47.2411

Reference yield:

→ 2,3-dimethyl-4-chlorophenol (1570-76-9)

Guidance literature:

With sulfuric acid; copper(l) chloride;

upstream raw materials:

2,3-Dimethylphenol

sulfuryl dichloride

acetic acid

Downstream raw materials:

(R)-4-chloro-6-fluoro-5,6-dimethylcyclohexa-2,4-dienone

1-[3,5-Dichloro-4-(4-chloro-2,3-dimethyl-phenoxy)-phenyl]-3-((E)-3-ethoxy-acryloyl)-urea

3,5-Dichloro-4-(4-chloro-2,3-dimethyl-phenoxy)-phenylamine

6-Aminomethyl-4-chloro-2,3-dimethyl-phenol; hydrochloride

Refernces

• 1、 Sato, Yasuo,Yamada, Megumi,Yoshida, Satoshi,Soneda, Tomoko,Ishikawa, Midori,Nizato, Tetsutaro,Suzuki, Kokichi,Konno, Fukio. "Benzoxazole derivatives as novel 5-HT3 receptor partial agonists in the gut". . p. 3015 - 3021. Retrieved 2007/10/03.