N-(5-Fluoro-2-nitrophenyl)acetamide

Base Information

Chemical Name:N-(5-Fluoro-2-nitrophenyl)acetamide
CAS No.:345-14-2
Molecular Formula:C8H7FN2O3
Molecular Weight:198.154
Hs Code.:
DSSTox Substance ID:DTXSID30586367
Wikidata:Q82478479

Synonyms:N-(5-FLUORO-2-NITROPHENYL)ACETAMIDE;345-14-2;N-methylcarbonyl 2-nitro-5-fluoroaniline;SCHEMBL4908494;DTXSID30586367;VQGOCZPTZPDVHL-UHFFFAOYSA-N;MFCD09836765;AKOS005068080;N-(5-fluoro-2-nitrophenyl)-acetamide;MCULE-9679523869;DB-361437;N-(5-Fluoro-2-nitrophenyl)acetamide, 98%;G67354

Suppliers and Price of N-(5-Fluoro-2-nitrophenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-(5-Fluoro-2-nitrophenyl)acetamide

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:198.04407025
Heavy Atom Count:14
Complexity:241

Purity/Quality:: 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=C(C=CC(=C1)F)[N+](=O)[O-]

Technology Process of N-(5-Fluoro-2-nitrophenyl)acetamide

There total 6 articles about N-(5-Fluoro-2-nitrophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 351-28-0
N-(3-fluorophenyl)acetamide

: 345-14-2
N-methylcarbonyl 2-nitro-5-fluoroaniline

: 345-30-2
3'-fluoro-4'-nitroacetanilide

Guidance literature:: With sulfuric acid; guanidine nitrate; In water; at -10 ℃; for 6h; Inert atmosphere;
DOI:10.1002/ejoc.201500795

Reference yield:

: 2369-11-1
5-fluoro-2-nitroaniline

: 108-24-7
acetic anhydride

: 345-14-2
N-methylcarbonyl 2-nitro-5-fluoroaniline

Guidance literature:: With N,N-diethyl-N-isopropylamine; dmap; In tetrahydrofuran; at 20 ℃;

Reference yield:

: 372-19-0
meta-fluoroaniline

: 345-14-2
N-methylcarbonyl 2-nitro-5-fluoroaniline

: 345-30-2
3'-fluoro-4'-nitroacetanilide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium acetate / water / 1 h / 0 °C / Inert atmosphere

2: sulfuric acid; guanidine nitrate / water / 6 h / -10 °C / Inert atmosphere

With sulfuric acid; sodium acetate; guanidine nitrate; In water;
DOI:10.1002/ejoc.201500795