m-Tolylhydrazine

Base Information

• Chemical Name: m-Tolylhydrazine
• CAS No.: 536-89-0
• Molecular Formula: C7H10N2
• Molecular Weight: 122.17
• Hs Code.: 2928000090
• European Community (EC) Number: 208-650-9
• UNII: SH79LJ6UD6
• DSSTox Substance ID: DTXSID60201819
• Nikkaji Number: J134.589C
• Wikidata: Q83075039
• Mol file: 536-89-0.mol

Synonyms:m-Tolylhydrazine;536-89-0;(3-methylphenyl)hydrazine;Hydrazine, (3-methylphenyl)-;3-METHYLPHENYLHYDRAZINE;(3-methyl-phenyl)-hydrazine;EINECS 208-650-9;AI3-15420;m-Tolylhydrazin;m-toluidine amine;m-tolyl hydrazine;m-Tolyl-hydrazine;1-m-tolylhydrazine;3-methyl-phenylhydrazine;SCHEMBL8318;SH79LJ6UD6;1-(3-Methylphenyl)hydrazine;1-(3-Methylphenyl)hydrazine #;DTXSID60201819;BBL012136;MFCD00047815;STK803070;AKOS002680135;BS-23650;BB 0249772;FT-0616172;A870654

Chemical Property of m-Tolylhydrazine

Chemical Property:

• Melting Point: 192-193 °C (decomp)
• Refractive Index: 1.5890
• Boiling Point: 243.8 °C at 760 mmHg
• PKA: 5.35±0.10(Predicted)
• Flash Point: 116 °C
• PSA: 38.05000
• Density: 1.087 g/cm³
• LogP: 2.85590
• Water Solubility.: Slightly soluble in water.
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 122.084398327
• Heavy Atom Count: 9
• Complexity: 83

Purity/Quality:

97% ^*data from raw suppliers

M-Tolylhydrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
• Hazard Codes: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
• Statements: 20/21/22
• Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC=C1)NN
• Uses: m-Tolylhydrazine is used as pharmaceutical intermediate. It reacts with cyclohexanone and obtain the 7-methyl-1,2,3,4-tetrahydro-carbazole.

Technology Process of m-Tolylhydrazine

There total 9 articles about m-Tolylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-amino-3-methylbenzene (108-44-1) → m-tolylhydrazine (536-89-0)

Guidance literature:

With tin(ll) chloride; sodium nitrite; Multistep reaction;

DOI:10.1007/BF00522729

Reference yield:

1-chloro-3-methylbenzene (108-41-8) → m-tolylhydrazine (536-89-0)

Guidance literature:

With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; N-[2-(di(1-adamantyl)phosphino)phenyl]morpholine; hydrazine hydrate; sodium t-butanolate; In toluene; at 90 ℃; for 1h; Inert atmosphere; Glovebox;

DOI:10.1016/j.bmcl.2015.11.022

Reference yield:

3-Iodotoluene (625-95-6) → m-tolylhydrazine (536-89-0)

Guidance literature:

With potassium phosphate; copper(l) iodide; hydrazine hydrate; at 120 ℃; for 6h; Sealed tube; Inert atmosphere;

DOI:10.1016/j.tet.2012.11.014

upstream raw materials:

3-methylbenzene diazonium

m-toluenediazonium chloride

1-amino-3-methylbenzene

hydrogenchloride

Downstream raw materials:

5-methyl-2-m-tolyl-1,2-dihydro-pyrazol-3-one

propionic acid-(N'-m-tolyl-hydrazide)

benzaldehyde m-tolylhydrazone

2-(m-methylphenyl)-4-phenylthiosemicarbazide